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Tepezza Disease Interactions

There are 2 disease interactions with Tepezza (teprotumumab).

Moderate

Teprotumumab (applies to Tepezza) diabetes

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Diabetes Mellitus

The use of teprotumumab may increase blood glucose levels. Care should be exercised when using this agent in patients with preexisting diabetes or impaired glucose tolerance and they should have appropriate glycemic control prior to initiating treatment. It is recommended to monitor patients for elevated blood glucose and symptoms of hyperglycemia and to manage patients according to clinical guidelines.

References

  1. "Product Information. Tepezza (teprotumumab)." Horizon Therapeutics USA Inc (2020):
Moderate

Teprotumumab (applies to Tepezza) IBD

Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Inflammatory Bowel Disease

The use of teprotumumab may cause an exacerbation of preexisting inflammatory bowel disease (IBD). Care should be exercised when using this agent in patients with IBD. It is recommended to monitor patients for flare of disease and to consider treatment discontinuation if IBD exacerbation is suspected.

References

  1. "Product Information. Tepezza (teprotumumab)." Horizon Therapeutics USA Inc (2020):

Tepezza drug interactions

There are 46 drug interactions with Tepezza (teprotumumab).


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.