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RotaShield (rotavirus vaccine) Disease Interactions

There are 2 disease interactions with RotaShield (rotavirus vaccine):

Major

Rotavirus Vaccine (Includes RotaShield) ↔ Immunodeficiency

Severe Potential Hazard, Moderate plausibility

Applies to: Immunodeficiency, Bone Marrow Depression/Low Blood Counts, Lymphoma

The safety and efficacy of rotavirus vaccine in infants with known primary or secondary immunodeficiencies, including HIV, infants in immunosuppressant therapy, or infants with malignant neoplasm affecting the bone marrow or lymphatic system has not been established. Caution is advised when considering wether to administer this vaccine to such patients or patients with immunodeficient close contacts as there is a potential of transmission of the virus through shedding in stools after vaccination (peak excretion occurring around day 7 after first dose).

Moderate

Rotavirus Vaccine (Includes RotaShield) ↔ Gi Disorders

Moderate Potential Hazard, Moderate plausibility

Applies to: Diarrhea, Vomiting

The administration of the rotavirus vaccine should be delayed in infants suffering from acute diarrhea or vomiting. Additionally, the effectiveness of this vaccine has not been evaluated in infants with chronic gastrointestinal disorders.

RotaShield (rotavirus vaccine) drug Interactions

There are 218 drug interactions with RotaShield (rotavirus vaccine)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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