Rotarix (rotavirus vaccine) Disease Interactions
There are 2 disease interactions with Rotarix (rotavirus vaccine):
Rotavirus Vaccine (Includes Rotarix) ↔ Immunodeficiency
Severe Potential Hazard, Moderate plausibility
Applies to: Immunodeficiency, HIV Infection, Bone Marrow Depression/Low Blood Counts, Lymphoma
The safety and efficacy of rotavirus vaccine in infants with known primary or secondary immunodeficiencies, including HIV, infants in immunosuppressant therapy, or infants with malignant neoplasm affecting the bone marrow or lymphatic system has not been established. Caution is advised when considering wether to administer this vaccine to such patients or patients with immunodeficient close contacts as there is a potential of transmission of the virus through shedding in stools after vaccination (peak excretion occurring around day 7 after first dose).
Rotavirus Vaccine (Includes Rotarix) ↔ Gi Disorders
Moderate Potential Hazard, Moderate plausibility
Applies to: Diarrhea, Vomiting, Infectious Diarrhea/Enterocolitis/Gastroenteritis
The administration of the rotavirus vaccine should be delayed in infants suffering from acute diarrhea or vomiting. Additionally, the effectiveness of this vaccine has not been evaluated in infants with chronic gastrointestinal disorders.
Rotarix (rotavirus vaccine) drug Interactions
There are 196 drug interactions with Rotarix (rotavirus vaccine)
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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