Rabies immune globulin, human Disease Interactions
There are 2 disease interactions with rabies immune globulin, human.
Rabies (applies to rabies immune globulin, human) antibody response
Major Potential Hazard, High plausibility. Applicable conditions: Immunodeficiency
Patients with primary or acquired deficient/impaired immune response (immunosuppressive therapy, genetic, splenic dysfunction, immunodeficiency disorders) may have reduced antibody response to immunizations. Deferral of immunosuppressive therapy may be considered pending completion of post-exposure therapy unless essential for treatment of other conditions.
Vaccines (applies to rabies immune globulin, human) IM injection
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Thrombocytopenia, Thrombocytopathy, Coagulation Defect
In patients with thrombocytopenia or coagulation disorders, IM injections may produce bleeding and hematomas. Patients with a platelet count less than 50,000/mm3 are at an increased risk. Caution is advised if the vaccine (e.g., plague vaccine; hepatitis A and B vaccines; aluminum-adsorbed DTaP, DTP, DT, or Td) must be administered IM. The risk of bleeding may be minimized by vaccination immediately after the administration of replacement factor, use of a 23-gauge (or smaller) needle, and immediate application of direct pressure to the vaccination site for at least 2 minutes.
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Rabies immune globulin, human drug interactions
There are 24 drug interactions with rabies immune globulin, human.
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- Drug class: immune globulins
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Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
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