Olezarsen Disease Interactions
There are 2 disease interactions with olezarsen.
Olezarsen (applies to olezarsen) liver disease
Moderate Potential Hazard, Moderate plausibility.
The safety and efficacy of olezarsen in patients with moderate or severe liver dysfunction have not been established. No dose adjustment is recommended in patients with mild liver dysfunction.
References (1)
- (2024) "Product Information. Tryngolza Autoinjector (olezarsen)." Ionis Pharmaceuticals, Inc.
Olezarsen (applies to olezarsen) renal dysfunction
Moderate Potential Hazard, Moderate plausibility.
The safety and efficacy of olezarsen in patients with severe renal dysfunction or end-stage renal disease have not been established. No dose adjustment is recommended in patients with mild to moderate renal dysfunction.
References (1)
- (2024) "Product Information. Tryngolza Autoinjector (olezarsen)." Ionis Pharmaceuticals, Inc.
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- Drug class: miscellaneous antihyperlipidemic agents
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
