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Galafold Disease Interactions

There is 1 disease interaction with Galafold (migalastat).

Moderate

Migalastat (applies to Galafold) renal dysfunction

Moderate Potential Hazard, Moderate plausibility.

Migalastat is substantially excreted by the kidneys. No dosage adjustment is required in patients with mild to moderate renal impairment (eGFR at least 30 mL/min/1.73 m2 and above). Migalastat is not recommended for use in patients with severe renal impairment or end-stage renal disease requiring dialysis. Systemic exposure was significantly increased in subjects with severe renal impairment (eGFR less than 30 mL/min/1.73 m2). Migalastat has not been studied in patients with Fabry disease who have an eGFR less than 30 mL/min/1.73 m2. Care is recommended when using this agent in patients with renal impairment.

References

  1. (2018) "Product Information. Galafold (migalastat)." Amicus Therapeutics U.S., Inc.

Galafold drug interactions

There is 1 drug interaction with Galafold (migalastat).

Galafold alcohol/food interactions

There is 1 alcohol/food interaction with Galafold (migalastat).

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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