Galafold Disease Interactions
There is 1 disease interaction with Galafold (migalastat).
Migalastat (applies to Galafold) renal dysfunction
Moderate Potential Hazard, Moderate plausibility.
Migalastat is substantially excreted by the kidneys. No dosage adjustment is required in patients with mild to moderate renal impairment (eGFR at least 30 mL/min/1.73 m2 and above). Migalastat is not recommended for use in patients with severe renal impairment or end-stage renal disease requiring dialysis. Systemic exposure was significantly increased in subjects with severe renal impairment (eGFR less than 30 mL/min/1.73 m2). Migalastat has not been studied in patients with Fabry disease who have an eGFR less than 30 mL/min/1.73 m2. Care is recommended when using this agent in patients with renal impairment.
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Galafold drug interactions
There is 1 drug interaction with Galafold (migalastat).
Galafold alcohol/food interactions
There is 1 alcohol/food interaction with Galafold (migalastat).
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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