Methylene blue Disease Interactions
There are 2 disease interactions with methylene blue.
Methylene blue (applies to methylene blue) methemoglobinemia in G-6-PD
Major Potential Hazard, High plausibility. Applicable conditions: G-6-PD Deficiency
The use of methylene blue is contraindicated for the treatment of methemoglobinemia in patients with glucose-6-phosphate deficiency (G-6-PD). Methylene blue will not reverse the condition in patients with G-6-PD and may precipitate acute hemolysis in these patients.
Methylene blue (applies to methylene blue) renal dysfunction
Moderate Potential Hazard, High plausibility.
Methylene blue is reduced in tissues to leukomethylene blue, and both are excreted by the kidney. The serum concentrations of methylene blue and leukomethylene blue may be increased in patients with impaired renal function. Therapy with methylene blue should be avoided in patients with severe renal impairment and administered cautiously in patients with mild to moderate renal impairment. Dosage adjustments may be necessary.
Methylene blue drug interactions
There are 196 drug interactions with methylene blue.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
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