Levonordefrin/mepivacaine Disease Interactions
There are 2 disease interactions with levonordefrin / mepivacaine.
Levonordefrin (applies to levonordefrin/mepivacaine) vasoconstrictor
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Heart Disease, Cardiovascular Disease, Thyrotoxicosis, Diabetes Mellitus
Compounds containing levonordefrin, a sympathomimetic amine used as a vasoconstrictor in local anesthetic solutions, should be used with extreme caution in the presence of disease which may adversely affect the patient's cardiovascular system. Close monitoring is recommended in patients whose medical history and physical evaluation suggest the existence of hypertension, arteriosclerotic heart disease, cerebral vascular insufficiency, heart block, thyrotoxicosis, and diabetes.
Mepivacaine (applies to levonordefrin/mepivacaine) arrhythmias
Moderate Potential Hazard, Moderate plausibility.
Mepivacaine should be used with caution in patients with a history of severe disturbances of cardiac rhythm or heart block. Care should be exercised when using this agent in patients with theses conditions.
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Levonordefrin/mepivacaine drug interactions
There are 246 drug interactions with levonordefrin / mepivacaine.
Levonordefrin/mepivacaine alcohol/food interactions
There is 1 alcohol/food interaction with levonordefrin / mepivacaine.
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More about levonordefrin / mepivacaine
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.