Grisactin 250 Disease Interactions
There are 3 disease interactions with Grisactin 250 (griseofulvin).
Griseofulvin (applies to Grisactin 250) hepatic dysfunction
Major Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
The use of griseofulvin is contraindicated in patients with hepatocellular failure, as animal data has shown that this drug may cause hepatocellular necrosis. The use of griseofulvin has not been adequately studied in patients with liver disease, although it is known that griseofulvin is primarily metabolized by the liver. Therapy with griseofulvin should be administered very cautiously in patients with liver impairment, and the dosing adjusted or discontinued according to clinical response.
Griseofulvin (applies to Grisactin 250) porphyria
Major Potential Hazard, High plausibility.
The use of griseofulvin is contraindicated in patients with porphyria. Griseofulvin has been shown to cause disturbances in porphyrin metabolism in laboratory animals.
Griseofulvin (applies to Grisactin 250) lupus erythematosus
Moderate Potential Hazard, Moderate plausibility.
The use of griseofulvin has been associated with the development of lupus erythematosus and lupus-like syndromes, as well as exacerbation of the disease. Griseofulvin therapy should be withdrawn in patients experiencing worsening of preexisting lupus until another cause can be identified.
Switch to professional interaction data
Grisactin 250 drug interactions
There are 274 drug interactions with Grisactin 250 (griseofulvin).
Grisactin 250 alcohol/food interactions
There is 1 alcohol/food interaction with Grisactin 250 (griseofulvin).
More about Grisactin 250 (griseofulvin)
- Check interactions
- Compare alternatives
- Drug images
- Side effects
- Dosage information
- During pregnancy
- Drug class: miscellaneous antifungals
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
See also:
Lamisil
Lamisil (terbinafine) is used to treat infections caused by fungus that affect the fingernails or ...
Ciclopirox topical
Ciclopirox topical is used for cutaneous candidiasis, onychomycosis, fingernail, onychomycosis ...
Taltz
Taltz (ixekizumab) is used to treat plaque psoriasis, psoriatic arthritis, and ankylosing ...
Lotrisone
Lotrisone is used to treat fungal skin infections such as athletes foot, jock itch, and ringworm ...
Miconazole topical
Miconazole topical is used for balanoposthitis, cutaneous candidiasis, intertrigo, oral thrush ...
Itraconazole
Itraconazole systemic is used for aspergillosis, aspergilloma, aspergillosis, invasive ...
Ketoconazole topical
Ketoconazole topical is used for androgenetic alopecia, cutaneous candidiasis, dandruff, seborrheic ...
Jublia
Jublia (efinaconazole) is an antifungal solution used to treat onychomycosis of the toenails ...
Penlac
Penlac nail lacquer (ciclopirox) is used to treat fungal infections of the toenails and ...
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.