Emapalumab Disease Interactions
There are 2 disease interactions with emapalumab.
Immunosuppressive agents (applies to emapalumab) infections
Major Potential Hazard, Moderate plausibility. Applicable conditions: Infection - Bacterial/Fungal/Protozoal/Viral
Serious and sometimes fatal infections have been reported in patients receiving immunosuppressive agents. Patients receiving immunosuppressants are at increased risk of developing bacterial, viral, fungal, and protozoal infections, and new or reactivated viral infections including opportunistic infections. Caution should be exercised when considering their use in patients with severe or chronic infections. It is recommended to interrupt therapy in patients who develop a new infection while undergoing treatment and to monitor these patients closely for any sign or symptom indicative of infection.
Emapalumab-lzsg (applies to emapalumab) vaccination
Moderate Potential Hazard, Moderate plausibility.
Do not administer live or live attenuated vaccines to patients receiving emapalumab-lzsg and for at least 4 weeks after the last dose of emapalumab-lzsg. Exercise care as the safety of immunization with live vaccines during or following therapy has not been studied.
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Emapalumab drug interactions
There are 185 drug interactions with emapalumab.
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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