Elvitegravir Disease Interactions
There are 2 disease interactions with elvitegravir.
Elvitegravir (applies to elvitegravir) hepatic dysfunction
Major Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
The use of elvitegravir is not recommended for use in patients with severe hepatic impairment (Child-Pugh Class C). No dosage adjustment is required in patients with mild (Child-Pugh Class A) or moderate (Child-Pugh Class B) hepatic impairment.
Elvitegravir (applies to elvitegravir) renal dysfunction
Major Potential Hazard, Moderate plausibility.
The use of elvitegravir is not recommended in patients with severe renal impairment (estimated creatinine clearance below 30 mL per minute). No dosage adjustment is recommended in patients with estimated creatinine clearance greater than or equal to 30 mL per minute.
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Elvitegravir drug interactions
There are 95 drug interactions with elvitegravir.
Elvitegravir alcohol/food interactions
There are 2 alcohol/food interactions with elvitegravir.
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- During pregnancy
- Drug class: integrase strand transfer inhibitor
- Breastfeeding
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
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