Calcium Disodium Versenate Disease Interactions
There are 3 disease interactions with Calcium Disodium Versenate (edetate calcium disodium).
Calcium EDTA (applies to Calcium Disodium Versenate) hepatitis
Major Potential Hazard, Moderate plausibility. Applicable conditions: Infectious Hepatitis
Edetate calcium disodium should not be given to patients with active hepatitis.
Calcium EDTA (applies to Calcium Disodium Versenate) renal dysfunction
Major Potential Hazard, High plausibility. Applicable conditions: Dehydration
The use of calcium EDTA is contraindicated in patients with anuria and active renal disease. Dose-related nephrotoxicity (usually reversible) associated with EDTA has included dysuria, oliguria, proteinuria, large renal epithelial cells in urine, renal insufficiency/failure, and acute tubular necrosis. Impaired renal function decreases the elimination of EDTA and may increase its nephrotoxicity. Adequate hydration (avoid excess hydration in patients with lead encephalopathy) and established urine flow prior to initiation of EDTA therapy is necessary. Clinical monitoring of renal function and calcium, phosphorus, and zinc levels is recommended.
EDTA (applies to Calcium Disodium Versenate) insulin/diabetes
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Diabetes Mellitus
EDTA may chelate zinc present in exogenous insulin and alter glucose concentrations and insulin requirements in patients with diabetes. Insulin dosages may need to be adjusted in diabetic patients administered EDTA.
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Calcium Disodium Versenate drug interactions
There are 38 drug interactions with Calcium Disodium Versenate (edetate calcium disodium).
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More about Calcium Disodium Versenate (edetate calcium disodium)
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- Drug class: antidotes
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Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.