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Calcium Disodium Versenate Side Effects

Generic Name: edetate calcium disodium

Note: This document contains side effect information about edetate calcium disodium. Some of the dosage forms listed on this page may not apply to the brand name Calcium Disodium Versenate.

For the Consumer

Applies to edetate calcium disodium: parenteral injection

Side effects include:

Injection site pain.

For Healthcare Professionals

Applies to edetate calcium disodium: compounding powder, injectable solution


Cardiovascular side effects have included hypotension and cardiac rhythm irregularities.[Ref]


Gastrointestinal side effects have included cheilosis, nausea, vomiting, anorexia, and excessive thirst.[Ref]


General side effects have included pain at the intramuscular injection site, fever, chills, malaise, and fatigue.[Ref]


Genitourinary side effects have included glycosuria, proteinuria, microscopic hematuria, and large epithelial cells in urinary sediment.[Ref]


Hematologic side effects have included transient bone marrow depression and anemia.[Ref]


Hepatic side effects are mild increases in SGOT and SGPT, which are common, and return to normal within 48 hours after cessation of therapy.[Ref]


Hypersensitivity side effects have included histamine-like reactions and rash.[Ref]


Immunologic side effects have included histamine-like reactions (sneezing, nasal congestion, and lacrimation) and rash.[Ref]


Metabolic side effects have included zinc deficiency and hypercalcemia.[Ref]


Musculoskeletal side effects have included myalgia and arthralgia.[Ref]

Nervous system

Nervous system side effects have included tremors, headache, numbness, and tingling.[Ref]


Renal side effects have included acute necrosis of proximal tubules (which may result in fatal nephrosis) and infrequent changes in distal tubules and glomeruli.[Ref]


1. "Product Information. Calcium Disodiuim Versenate (edetate calcium disodium)." 3M Pharmaceuticals, St Paul, MN.

Some side effects of Calcium Disodium Versenate may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

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