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Rescriptor (delavirdine) Disease Interactions

There are 2 disease interactions with Rescriptor (delavirdine):

Moderate

Delavirdine (Includes Rescriptor) ↔ Achlorhydria

Moderate Potential Hazard, High plausibility

Applies to: Achlorhydria

Patients with achlorhydria should take delavirdine with an acidic beverage such as orange or cranberry juice, presumably to improve absorption. Although the effects of acidic beverages on delavirdine absorption have not been studied, delavirdine is known to be poorly soluble when pH is greater than 3.

References

  1. "Product Information. Rescriptor (delavirdine)." Pharmacia and Upjohn, Kalamazoo, MI.
Moderate

Delavirdine (Includes Rescriptor) ↔ Liver Disease

Moderate Potential Hazard, High plausibility

Applies to: Liver Disease

Delavirdine is primarily metabolized by the liver. Patients with liver disease may be at greater risk for toxicities and adverse effects from delavirdine due to decreased drug clearance. Therapy with delavirdine should be administered cautiously in patients with liver disease.

References

  1. "Product Information. Rescriptor (delavirdine)." Pharmacia and Upjohn, Kalamazoo, MI.

Rescriptor (delavirdine) drug Interactions

There are 710 drug interactions with Rescriptor (delavirdine)

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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