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Charcoal/simethicone Disease Interactions

There are 2 disease interactions with charcoal / simethicone.

Major

Charcoal (applies to charcoal/simethicone) gastrointestinal obstruction

Major Potential Hazard, Moderate plausibility.

Charcoal (with or without sorbitol) should not be used in the presence of a stomach or intestinal obstruction or absence of active bowel sounds. Delayed GI transit time or constipation can result in failure to excrete a drug- charcoal complex and may result in increased toxicity.

Major

Charcoal (applies to charcoal/simethicone) seizures

Major Potential Hazard, Moderate plausibility. Applicable conditions: Altered Consciousness

Charcoal should not be administered in poison victims that are unconscious or having convulsions.

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Charcoal/simethicone drug interactions

There are 84 drug interactions with charcoal / simethicone.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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