Bremelanotide Disease Interactions
There are 3 disease interactions with bremelanotide:
Bremelanotide (applies to bremelanotide) hypertension/CV disease
Major Potential Hazard, Moderate plausibility. Applicable conditions: Cardiovascular Disease
Bremelanotide is contraindicated in patients who have uncontrolled hypertension or known cardiovascular disease, as it transiently increases blood pressure and reduces heart rate after each dose. Before initiating bremelanotide, and periodically during treatment, consider the patient's cardiovascular risk and ensure blood pressure is well-controlled.
Bremelanotide (applies to bremelanotide) severe hepatic impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Liver Disease
Bremelanotide has not been evaluated in patients with severe hepatic impairment and should be used with caution in these patients (Child-Pugh C; score 10-15), because they may have an increase in the incidence and severity of adverse reactions (e.g., nausea and vomiting). No dosing adjustments are recommended for patients with mild to moderate (Child-Pugh A and B; score 5-9) hepatic impairment.
Bremelanotide (applies to bremelanotide) severe renal impairment
Moderate Potential Hazard, Moderate plausibility. Applicable conditions: Renal Dysfunction
Use bremelanotide with caution in patients with severe (eGFR <30 mL/min/1.73 m2) renal impairment, because these patients may have an increase in the incidence and severity of adverse reactions (e.g., nausea and vomiting). No dosing adjustments are recommended for patients with mild to moderate (eGFR 30-89 mL/min/1.73 m2) renal impairment.
Bremelanotide drug interactions
There is 1 drug interaction with bremelanotide
Bremelanotide alcohol/food interactions
There are 2 alcohol/food interactions with bremelanotide
More about bremelanotide
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- En Español
- 6 Reviews
- Drug class: melanocortin receptor agonists
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
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