Amphotericin b Disease Interactions
There is 1 disease interaction with amphotericin b:
Ampho B (Includes Amphotericin b) ↔ Anemia
Moderate Potential Hazard, High plausibility
Applies to: Anemia
Intravenous amphotericin B therapy may depress erythropoietin and red blood cell production and commonly causes a normocytic, normochromic anemia. Although the anemia is well tolerated by most patients and usually reverses completely within several months of stopping therapy, it may be problematic in patients with preexisting anemia. Intravenous therapy with amphotericin B should be administered cautiously in anemic patients or those predisposed to anemia. Frequent monitoring of blood counts and hemoglobin concentrations are recommended.
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- Miller R, Bates J "Amphotericin B toxicity." Ann Intern Med 71 (1969): 1089-95
- Lyman C, Walsh T "Systemically administered antifungal agents." Drugs 44 (1992): 9-35
amphotericin b drug Interactions
There are 197 drug interactions with amphotericin b
Drug Interaction Classification
The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
|Major||Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderate||Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minor||Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
Do not stop taking any medications without consulting your healthcare provider.
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