Technetium tc 99m tilmanocept (Injection)
tek-NEE-shee-um Tc 99m til-MAN-oh-sept
Medically reviewed on June 7, 2018
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Diagnostic Agent, Radiopharmaceutical Imaging
Uses For This Medicine
Technetium Tc 99m tilmanocept injection is a radiopharmaceutical. Radiopharmaceuticals are radioactive agents, which may be used to find and treat certain diseases or to study the function of the body's organs.
Technetium Tc 99m tilmanocept injection is used to find lymph node in patients with solid tumors. It is also used to find sentinel lymph nodes in patients with breast, skin or oral cavity cancer.
Technetium tc 99m tilmanocept is to be given only by or under the direct supervision of a doctor with specialized training in nuclear medicine.
Before Using This Medicine
In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to technetium tc 99m tilmanocept or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of technetium Tc 99m tilmanocept injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of technetium Tc 99m tilmanocept injection in the elderly.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:
- Allergy to dextran and other forms of dextran (eg, iron dextran)—Use with caution. May cause allergic reaction to occur again.
Proper Use of This Medicine
A doctor or other trained health professional will give you technetium tc 99m tilmanocept. Depending on your medical problem, technetium tc 99m tilmanocept is given as a shot under your skin, into your skin, around the tumor, or below the areola of the breast.
Precautions While Using This Medicine
It is very important that your doctor check you closely while you are receiving technetium tc 99m tilmanocept. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it.
Technetium tc 99m tilmanocept may cause serious allergic reactions. Check with your doctor right away if you have a rash, itching, swelling of the face, tongue, and throat, trouble breathing, or chest pain after you get the injection.
You will be exposed to radiation when you are given technetium tc 99m tilmanocept. This could increase the risk of cancer, especially for children. Talk with your doctor if you have concerns about this.
If you are a woman who can get pregnant, technetium tc 99m tilmanocept should be given within 10 days after the start of your monthly period or a pregnancy test should be performed within 48 hours before you receive technetium tc 99m tilmanocept.
Tell your doctor if you are breastfeeding. Do not breastfeed for at least 60 hours after you receive technetium tc 99m tilmanocept. The milk should be pumped and thrown away.
This Medicine Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
Incidence not known
- Difficulty with breathing or swallowing
- fast heartbeat
- skin itching, rash, or redness
- swelling of the face, throat, or tongue
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Pain or irritation at the injection site
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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