Generic Name: secretin (Intravenous route)
Medically reviewed by Drugs.com. Last updated on May 28, 2019.
The SecreFlo brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Endocrine-Metabolic Agent
Uses for Secreflo
Secretin injection is used for the stimulation of pancreas secretions to help diagnose or find problems in the pancreas and to help identify the ampulla of Vater and accessory papilla during endoscopy. It is also used to help in the diagnosis of gastrinoma (tumor of the bowel or pancreas).
This medicine is to be given only by or under the supervision of a doctor.
Before using Secreflo
In deciding to use a diagnostic test, any risks of the test must be weighed against the good it will do. This is a decision you and your doctor will make. Also, other things may affect test results. For this test, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of secretin injection in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of secretin injection in the elderly. However, elderly patients are more sensitive to the effects of this medicine than younger adults.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are receiving this diagnostic test, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Receiving this diagnostic test with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
- Oxitropium Bromide
- Pipenzolate Bromide
Interactions with food/tobacco/alcohol
Other medical problems
The presence of other medical problems may affect the use of this diagnostic test. Make sure you tell your doctor if you have any other medical problems, especially:
- Inflammatory bowel disease or
- Vagotomy (bowel surgery)—May decrease the response to pancreas stimulation testing causing a false diagnosis.
- Liver disease, alcoholic or other—May mask existing disease of the pancreas.
Proper use of Secreflo
This section provides information on the proper use of a number of products that contain secretin. It may not be specific to Secreflo. Please read with care.
A doctor will give you this medicine in a hospital. This medicine is given through a needle placed into one of your veins.
You should not eat or drink for at least 12 to 15 hours before receiving this medicine.
Do not take an H2 blocker at least 2 days before receiving this medicine.
Precautions while using Secreflo
It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly and to check for unwanted effects.
Do not use anticholinergic medicines together with secretin injection. This may decrease the response to pancreas stimulation testing, which may cause a false diagnosis of having a pancreas disease.
Do not also use stomach medicines, such as a proton pump inhibitor and an H2 blocker together with secretin injection. This may cause an increase in the response to pancreas stimulation testing, which may lead to a false diagnosis of having gastrinoma (tumor in the bowel or pancreas).
Secreflo side effects
- Feeling of warmth
- redness of the face, neck, arms and occasionally, upper chest
- stomach upset
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