Skip to Content

potassium phosphate (Intravenous route)

poe-TAS-ee-um FOS-fate

Available Dosage Forms:

  • Solution

Therapeutic Class: Parenteral Electrolyte, Potassium

Uses For potassium phosphate

Potassium phosphate injection is a phosphate supplement that is used to treat or prevent hypophosphatemia (low phosphorus in the blood). It is also used as an additive in the preparation of fluid formula injections.

potassium phosphate is to be given only by or under the direct supervision of a doctor.

Before Using potassium phosphate

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For potassium phosphate, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to potassium phosphate or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


No information is available on the relationship of age to the effects of potassium phosphate injection in the pediatric population. Safety and efficacy have not been established.


No information is available on the relationship of age to the effects of potassium phosphate in geriatric patients.


Pregnancy Category Explanation
All Trimesters C Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breast Feeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other Medical Problems

The presence of other medical problems may affect the use of potassium phosphate. Make sure you tell your doctor if you have any other medical problems, especially:

  • Adrenal problems, severe or
  • Heart disease or
  • Heart rhythm problems or
  • Kidney disease, severe—Use with caution. May make these conditions worse.
  • Hyperkalemia (high blood potassium) or
  • Hyperphosphatemia (high blood phosphorus) or
  • Hypocalcemia (low calcium in the blood)—Should not be used in patients with these conditions.
  • Kidney disease—Use with caution. The effect may be increased because of slower removal of the medicine from the body.

Proper Use of potassium phosphate

A nurse or other trained health professional will give you potassium phosphate in a hospital. potassium phosphate is given through a needle placed in a vein.

Precautions While Using potassium phosphate

Your doctor will check your progress closely while you are receiving potassium phosphate. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to receive it. Blood tests may be needed to check for unwanted effects.

potassium phosphate contains aluminum which can cause harm especially to premature babies. Talk to your doctor if you have concerns about this.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

potassium phosphate Side Effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

Incidence not known
  • Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
  • chest pain or discomfort
  • confusion
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • fast, slow, or irregular heartbeat
  • muscle cramps in the hands, arms, feet, legs, or face
  • no muscle tone or movement
  • numbness and tingling around the mouth, fingertips, or feet
  • pounding or rapid pulse
  • shortness of breath
  • unusual tiredness or weakness
  • weakness and heaviness of the legs

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

See also: Side effects (in more detail)

The information contained in the Truven Health Micromedex products as delivered by is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products.

Copyright 2016 Truven Health Analytics, Inc. All Rights Reserved.