Generic Name: antivenin (CROTALIDAE) POLYVALENT IMMUNE FAB (Intravenous route)
an-tye-VEN-in (kroe-TAL-i-dee) pol-ee-VAY-lent i-MUNE fab
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Antivenom
Uses For Crofab
Pit viper antivenin is a medicine used to treat the bites of certain poisonous snakes called pit vipers (crotalids), which are native to North America. This particular pit viper antivenin is made from the blood of sheep and is used to treat the bites of the following types of pit viper: the Western Diamondback, Eastern Diamondback, and Mojave rattlesnakes, and the Copperhead snake or Water Moccasin.
Pit viper antivenin is to be used only by or under the supervision of a doctor.
Before Using Crofab
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Although there is no specific information comparing use of pit viper antivenin in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.
Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of pit viper antivenin in the elderly with use in other age groups.
|All Trimesters||C||Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.|
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with Medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with Food/Tobacco/Alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other Medical Problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Snake bite, previous— During previous treatment, your body may have developed antibodies (proteins produced by the immune system that help the body fight infection and are involved in allergic reactions), which may cause a serious reaction with current treatment
Proper Use of Crofab
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Crofab Side Effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:More common
- Unexplained bleeding or bruising
- difficulty in breathing
- difficulty in swallowing
- dizziness or lightheadedness
- fast heartbeat
- hives or welts
- itching of skin
- joint pain
- large, hive-like swellings on the eyelids, face, lips, mouth, and/or tongue
- muscle pain
- noisy breathing
- redness of skin
- shortness of breath
- skin rash
Check with your doctor as soon as possible if any of the following side effects occur:Less common
- Areas of pain, redness, and swelling
- chest pain
- discharge from wound
- pain, tenderness, and warmth at wound site
- unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
- Back pain
- generalized numbness, tingling, crawling, prickling, “pins and needles” feelings
- hard bumps under the skin
- loss of appetite
- numbness and tingling around the mouth
- increased amount of phlegm
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