Skip to Content

Medications for Sinus Symptoms

About Sinus Symptoms:  Sinus symptoms are associated with a variety of upper respiratory tract disorders including the common cold, sinus infection, hay fever and are characterized by congestion of the nasal mucous membrane, watery nasal rhinorrhea, facial pain especially around eyes, nose & forehead, earache, dental pain, sneezing, fever and bad breath.

Drugs Used to Treat Sinus Symptoms

The following list of medications are in some way related to, or used in the treatment of this condition.

Drug name Rx / OTC Pregnancy CSA Alcohol Reviews Rating Activity
acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine N N X Add review 0.0

Generic name: acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine systemic

Brand names:  Tylenol Cold Multi-Symptom Nighttime, Cold Multi-Symptom (Nighttime), Comtrex Nighttime Cold & Cough, Theraflu Nighttime Severe Cold & Cough Caplets, Tylenol Cold Head Congestion Nighttime …show all

Drug class: upper respiratory combinations

For consumers: dosage, interactions,

Advil Children's Cold C N X Add review 0.0

Generic name: ibuprofen / pseudoephedrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

Advil Congestion Relief D N X Add review 0.0

Generic name: ibuprofen / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: interactions, side effects

Advil Sinus Congestion & Pain D N X Add review 0.0

Generic name: ibuprofen / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: interactions, side effects

Aldex G C N Add review 0.0

Generic name: guaifenesin / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Allerest No Drowsiness N N X Add review 0.0

Generic name: acetaminophen / pseudoephedrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Allergy Multi-Symptom N N X Add review 0.0

Generic name: acetaminophen / chlorpheniramine / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Aquatab D C N Add review 0.0

Generic name: guaifenesin / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Chlorex A C N X Add review 0.0

Generic name: chlorpheniramine / phenylephrine / phenyltoloxamine systemic

Drug class: upper respiratory combinations

For consumers: interactions, side effects

chlorpheniramine / phenylephrine / phenyltoloxamine C N X Add review 0.0

Generic name: chlorpheniramine / phenylephrine / phenyltoloxamine systemic

Brand names:  Chlorex A, Nalex-A

Drug class: upper respiratory combinations

For consumers: interactions,

Cold Multi-Symptom (Nighttime) N N X Add review 0.0

Generic name: acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Comtrex Cold & Cough N N X Add review 0.0

Generic name: acetaminophen / dextromethorphan / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Comtrex Cold and Cough Maximum Strength N N X Add review 0.0

Generic name: acetaminophen / dextromethorphan / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Comtrex Flu Therapy N N X Add review 0.0

Generic name: acetaminophen / chlorpheniramine / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Comtrex Nighttime Cold & Cough N N X Add review 0.0

Generic name: acetaminophen / chlorpheniramine / dextromethorphan / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Comtrex Severe Cold & Sinus N N X Add review 0.0

Generic name: acetaminophen / chlorpheniramine / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Conex C N X Add review 0.0

Generic name: dexbrompheniramine / pseudoephedrine systemic

Drug class: upper respiratory combinations

For consumers: interactions, side effects

Contac Cold + Flu (Day Formula) N N X Add review 0.0

Generic name: acetaminophen / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Contac Cold + Flu (Night Formula) N N X Add review 0.0

Generic name: acetaminophen / chlorpheniramine / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Crantex C N Add review 0.0

Generic name: guaifenesin / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

For professionals: Prescribing Information

D-Phen 1000 C N Add review 0.0

Generic name: guaifenesin / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Deconex C N Add review 0.0

Generic name: guaifenesin / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

Deconex IR C N Add review 0.0

Generic name: guaifenesin / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: dosage, interactions, side effects

dexbrompheniramine / phenylephrine C N X Add review 0.0

Generic name: dexbrompheniramine / phenylephrine systemic

Drug class: upper respiratory combinations

For consumers: interactions,

For professionals: A-Z Drug Facts

Dixaphedrine C N X Add review 0.0

Generic name: dexbrompheniramine / pseudoephedrine systemic

Drug class: upper respiratory combinations

For consumers: interactions, side effects

Alternative treatments for Sinus Symptoms

The following products are considered to be alternative treatments or natural remedies for Sinus Symptoms. Their efficacy may not have been scientifically tested to the same degree as the drugs listed in the table above. However there may be historical, cultural or anecdotal evidence linking their use to the treatment of Sinus Symptoms.

Legend

Rx Prescription Only
OTC Over the Counter
Rx/OTC Prescription or Over the Counter
Off Label This medication may not be approved by the FDA for the treatment of this condition.
Pregnancy Category
A Adequate and well-controlled studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).
B Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.
C Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
D There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use in pregnant women despite potential risks.
X Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use in pregnant women clearly outweigh potential benefits.
N FDA has not classified the drug.
Controlled Substances Act (CSA) Schedule
N Is not subject to the Controlled Substances Act.
1 Has a high potential for abuse. Has no currently accepted medical use in treatment in the United States. There is a lack of accepted safety for use under medical supervision.
2 Has a high potential for abuse. Has a currently accepted medical use in treatment in the United States or a currently accepted medical use with severe restrictions. Abuse may lead to severe psychological or physical dependence.
3 Has a potential for abuse less than those in schedules 1 and 2. Has a currently accepted medical use in treatment in the United States. Abuse may lead to moderate or low physical dependence or high psychological dependence.
4 Has a low potential for abuse relative to those in schedule 3. It has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 3.
5 Has a low potential for abuse relative to those in schedule 4. Has a currently accepted medical use in treatment in the United States. Abuse may lead to limited physical dependence or psychological dependence relative to those in schedule 4.
Alcohol
X Interacts with Alcohol.

Browse Treatment Options

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.