Comparing Sirolimus vs Tacrolimus
| Sirolimus | Tacrolimus |
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| Sirolimus | Tacrolimus |
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Prescription only
Prescribed for Lymphangioleiomyomatosis, Organ Transplant - Rejection Prophylaxis. Sirolimus may also be used for purposes not listed in this medication guide. |
Prescription only
Prescribed for Organ Transplant - Rejection Reversal, Organ Transplant - Rejection Prophylaxis, Nephrotic Syndrome, Graft Versus Host Disease, Crohn's Disease. Tacrolimus may also be used for... View more |
Related suggestions Organ Transplant, Rejection Prophylaxis
Popular comparisons
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| More about Sirolimus | More about Tacrolimus | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Sirolimus has an average rating of 6.0 out of 10 from a total of 8 ratings on Drugs.com. 38% of reviewers reported a positive effect, while 38% reported a negative effect. |
Tacrolimus has an average rating of 7.9 out of 10 from a total of 49 ratings on Drugs.com. 71% of reviewers reported a positive effect, while 12% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Sirolimus side effects |
View all Tacrolimus side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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Lower cost generic |
Lower cost generic |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Sirolimus prices |
View all Tacrolimus prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
| Rapamune | Astagraf XL, Envarsus XR, Prograf | ||||||||||||||||
| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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78 hours |
21.2 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 716 drugs are known to interact with Sirolimus:
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A total of 867 drugs are known to interact with Tacrolimus:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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| Disease Interactions | |||||||||||||||||
| First Approval Date | |||||||||||||||||
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September 15, 1999 |
April 08, 1994 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.