Comparing Orladeyo vs Takhzyro
| Orladeyo (berotralstat) | Takhzyro (lanadelumab) |
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| Orladeyo (berotralstat) | Takhzyro (lanadelumab) |
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Prescription only
Orladeyo is an oral, once-daily medication used to prevent angioedema attacks in adults and children 12 years and older with HAE. It is the only oral preventive treatment for HAE attacks currently... View more |
Prescription only
Takhzyro works by binding to a protein called kallikrein and inhibiting its activity and may be used to prevent hereditary angioedema (HAE) attacks in adults, adolescents, and children aged 2 years... View more |
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| More about Orladeyo (berotralstat) | More about Takhzyro (lanadelumab) | ||||||||||||||||
| Ratings & Reviews | |||||||||||||||||
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Orladeyo has an average rating of 6.7 out of 10 from a total of 3 ratings on Drugs.com. 33% of reviewers reported a positive effect, while 0% reported a negative effect. |
Takhzyro has an average rating of 9.8 out of 10 from a total of 4 ratings on Drugs.com. 100% of reviewers reported a positive effect, while 0% reported a negative effect. |
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| Side Effects Experienced by Users Side effects are reported in Drugs.com user reviews and not clinically verified. | |||||||||||||||||
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View all Orladeyo side effects |
View all Takhzyro side effects |
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| Drug Class | |||||||||||||||||
| Generic Availability | |||||||||||||||||
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N/A |
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| Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Orladeyo prices |
View all Takhzyro prices |
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| Dosage Forms | |||||||||||||||||
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| Brand Names | |||||||||||||||||
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N/A |
N/A |
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| Half Life Drug half-life is the time required for plasma concentration to reduce to half its original value. | |||||||||||||||||
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152 hours |
360 hours |
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| CSA Schedule 1 View glossary of CSA terms | |||||||||||||||||
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Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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| Pregnancy Category | |||||||||||||||||
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Summary unavailable. See the full pregnancy warnings document. |
Summary unavailable. See the full pregnancy warnings document. |
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| Drug Interactions | |||||||||||||||||
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A total of 525 drugs are known to interact with Orladeyo:
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A total of 3 drugs are known to interact with Takhzyro:
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| Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
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No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| Disease Interactions | |||||||||||||||||
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No known disease interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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| First Approval Date | |||||||||||||||||
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December 03, 2020 |
August 23, 2018 |
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| WADA Class View classifications | |||||||||||||||||
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N/A |
N/A |
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| More Information | |||||||||||||||||
| Patient Resources | |||||||||||||||||
| Professional Resources | |||||||||||||||||
| Related Treatment Guide | |||||||||||||||||
1 The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.