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Tirzepatide and Vomiting: What Users Say (Page 3)

Brand names: Mounjaro, Zepbound

Reviews for Tirzepatide

Commonly mentioned side effects
  • Jan...
  • Taken for less than 1 month
  • November 24, 2024

Tirzepatide for Type 2 Diabetes "I've only had 2 shots and 2 days until the next one. I find it very convenient to administer. However, I have had some nasty side effects! I've had diarrhea, nausea, vomiting, fatigue. I will continue taking the medication hoping the side effects will 'calm down.'"

7 / 10
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  • Cat...
  • Taken for 6 months to 1 year
  • August 11, 2024

Tirzepatide for Type 2 Diabetes "I have been using Mounjaro for a year now, with order coming from cosmicaesthetics.com. First time I had negative effects, nausea, constant vomiting, and tiredness. My body got used to it, and ever since, my blood sugar has been in check. I really advise anyone who is diabetic."

8 / 10
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  • BOB...
  • Taken for 1 to 6 months
  • May 30, 2024

Tirzepatide for Type 2 Diabetes "Dropped 60 lbs! My numbers are nearly all under 100 now. Nausea and vomiting I was able to keep at bay with ginger chews or ginger gum. It suppressed my appetite, and I didn't want to overeat. Also, fewer cravings for sugary items."

9 / 10
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Frequently asked questions

  • Car...
  • Taken for 1 to 6 months
  • April 30, 2023

Tirzepatide "I have insulin resistance, and I have taken my first dose of 5 mg this week. I have never been so dizzy in my life. I have to force myself to eat and drink. I could totally go all day without eating or drinking. When I force myself to eat, I get very nauseous or actually vomit. I have daily Zofran, which helps just keep the edge off, but eating is so hard. I know I need to eat, but I can’t. It’s great because I have never been able to feel full, I would just eat until it physically hurts. Now the binge restriction cycle has ended. I have lost weight and have felt good on the 2.5 mg dose, I have just had mild nausea. Because it’s hard to eat, I doubt I have even really hit 1200 calories. I know my blood sugar has been low, and I can’t even drive without feeling unsafe. I got an IV, and that helped, but I do not want to do the next 3 doses of 5 mg. I’m calling my doctor this week to follow up and double-check what he thinks. Crackers and Core Power milk have helped."

10 / 10
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  • Sco...
  • Taken for 1 to 6 months
  • March 18, 2025

Tirzepatide for Type 2 Diabetes "So far, so good until yesterday. I think I ate too much, and then the stomach pain started, and diarrhea followed all night. As I tried to ingest water, I became nauseous and had to throw up, but that decreased the pain. I think I’m just getting used to the drug since this was my first dose of 7.5 mg pen."

7 / 10
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  • Kym...
  • Taken for 1 to 6 months
  • July 22, 2024

For Weight Loss (Obesity/Overweight) "Ok, so month 2. Started at 220, down to 208. Roughly 2 lbs a week. Which, in my opinion, is good. My gut/brain communication is back, and now my tummy has been telling my brain that it's full in a timely manner, and I have no overwhelming desire to finish what's on my plate. I can let it go. I've stopped compulsively overeating, and actually feel satisfied with a small meal. I take liquid vitamins to try and stave off the plateau. But I don't think it's coming for a while. My goal weight is 140 lbs. I'm 4'11' and solidly built, so 140 is healthy on me. I have not had any negative side effects. No tiredness, nausea, cramps, constipation, or vomiting. My allergies have calmed down a lot. And my hypoglycemia has mostly righted itself. Meaning, I only experience it now on the last two days before my next shot. I just went up to 7.5 mg today. So far so good. I feel excellent and usually experience a bit of relaxation and euphoria about an hour after. I hope the higher dose will fix the hypoglycemia."

10 / 10
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  • dee...
  • Taken for 1 to 6 months
  • November 30, 2022

Tirzepatide for Type 2 Diabetes "I have been on Mounjaro since Sep 2022. I started off with the 2.5 mg for about a month with no issues. My provider then moved me to 5 mg in October. Once again, no issues, and I started losing weight. 15 lbs in about 6 weeks. I was then moved up to 7.5 mg in November and have been miserable ever since. I have no appetite, severe constipation, major headaches, and vomiting, and I am now having issues with low blood pressure (causing lightheadedness, dizziness, and vision issues), which I believe is being caused by my never wanting to eat or drink anything. I have informed my provider of this, and she is now wanting to send me to a cardiologist to make sure my heart is working properly. She has also decided to lower my dosage back to 5 mg. I am hoping this change helps because so far, my type 2 diabetes is under control, and my sugars have been fantastic!"

7 / 10
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More FAQ

  • Dru...
  • Taken for 1 to 6 months
  • April 12, 2025

Tirzepatide for Type 2 Diabetes "Currently on 750 Mounjaro. 2nd injection on Wednesday, had a 17-hour episode of vomiting and diarrhea on Sunday afternoon into Monday morning. I did not take the 3rd injection the following Wednesday. By Friday, I had the hungry horrors and joint pain in my hips and knees. Weight loss about 25 lbs, and my A1C only came down from 7.5 to 7.1 in the 5 months I’ve been on Mounjaro. If you take these meds, please listen to your body and the way it reacts to these meds."

5 / 10
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  • me5...
  • Taken for 1 to 6 months
  • April 2, 2025

Tirzepatide for Type 2 Diabetes "Had to stop taking after 7 weeks of use. Total loss of appetite, very weak. When I try to eat, cannot do it due to gagging. The smell of foods upsets my stomach. Getting scary now, haven't used Mounjaro for 2 1/2 weeks and no improvement. No energy at all, hard to function."

3 / 10
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  • Mk6...
  • Taken for 1 to 6 months
  • March 10, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I started in January 2025 with the 2.5 dose. For the first two weeks, I experienced nausea and diarrhea off and on. For the last two weeks, I was fine. I am on my second week of 5 mg. The first week, I was so sick - I take the shot late Friday afternoon - I was in bed most of the day on Saturday with nausea and fatigue. I did vomit once. Sunday was the same. The rest of the week, I felt fine. Second shot last Friday - I was okay on Saturday - able to function but very nauseous. Woke up on Sunday and spent most of the day in bed due to nausea and fatigue. The anti-nausea medicine helps but not so much for me. Today I am functioning with some nausea. The benefits of this drug are obvious. I don't eat as much as I did before the medicine. I've lost 16 lbs so far. The nausea bothers me. I should be able to function and not get sick every weekend after a shot. I no longer have diarrhea - I am constipated instead. When I take Miralax, I cannot think about it or I get sick."

7 / 10
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  • Anonymous
  • Taken for less than 1 month
  • October 6, 2024

For Weight Loss (Obesity/Overweight) "Prescribed 1.25 mg as the first dose (15 u). Chose to take 10 units since I never took it before. Had confusion, which subsided with sugar. Vomited three hours later. Voice a little raspy. Felt better, and symptoms calmed after 8 hours. I ate basically low-carb before starting and think I should have been asked what my diet is prior to taking. I’m a nurse for 20 years, so I have knowledge regarding symptoms and medication. Wish I would have started with 5 units instead. This medicine drastically reduced my hunger immediately."

6 / 10
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  • Che...
  • Taken for 1 to 6 months
  • December 1, 2024

Tirzepatide for Type 2 Diabetes "Makes me feel full faster and longer, but with reflux. Sometimes I am still full from yesterday if I eat. It turns to nausea, then vomiting, with epigastric burning and abdominal pain lasting 15 minutes to 45 minutes. Even with Zofran and whatever else I can take. Then I can't sleep, of course, so I'm up till 4:00 or 5:00 AM. I have lost weight on the 10 mg under the doctors' and nurse practitioners' diabetic care. Then I can go a week or two weeks without any negative symptoms at all."

7 / 10
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  • Bri...
  • Taken for 6 months to 1 year
  • January 6, 2025

For Weight Loss (Obesity/Overweight) "I have been on tirzepatide for six months, and I have lost 20 lbs. I will be honest and say that I am not currently exercising, so I would most likely be losing more if I were. I am in my mid-50s. I was on Ozempic in the past and lost approximately 20 lbs on that medication. I definitely had more side effects while I was on Ozempic. I feel like tirzepatide is slower to work, but the side effects are less intense because of that. I still have mild side effects of nausea, some vomiting, and constipation, but none of the side effects were as bad as when I was on Ozempic."

8 / 10
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  • kee...
  • Taken for 1 to 2 years
  • April 18, 2025

Tirzepatide for Type 2 Diabetes "I've been on Rybelsus, Trulicity, and Ozempic with minimal results both on A1C and weight loss, and lots of stomach issues. Presently on Mounjaro 10 mg for the past year, having gradually increased dosage along the way. Side effects are constipation, and approximately every three weeks I'll have an episode of stomach pain, sulfur burps, and vomiting. It's usually in the middle of the night, throwing up dinner and anything else eaten that day, sitting on my stomach all day. Vomiting, severe sweating, chills. After that, it passes, and I feel perfectly fine until weeks later it happens again. I can tolerate this side effect, and A1C is much better."

8 / 10
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  • Me1...
  • Taken for 1 to 6 months
  • March 7, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I started off with 2.5 mg the first month. Second month is 5 mg. Today I take the 3rd needle from the package. Last night was the first time I was nauseous and vomiting. I don't know if it was from the medication, but that day I had eaten chips and chocolate. I had not since I started. I want to believe eating those led me to being sick. Burping started about 3 weeks ago but only lasts for a day. It has happened 3 times. Been stuck on the same weight for 2 weeks."

7 / 10
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  • SLB...
  • Taken for less than 1 month
  • March 13, 2023

Tirzepatide for Type 2 Diabetes "Had my first dose yesterday, 3/12/23, and today I have intense nausea, and it feels like a rock in my gut. I also have a prescription for an anti-nausea med, which I am not sure is working since I feel like throwing up. It did lower my BGM pretty well. I had previously tried Ozempic with horrible side effects of nausea and vomiting. I lasted the first week, so one dose. I do like the way Mounjaro is administered. I don't think the Ozempic was quite like that."

5 / 10
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  • BBr...
  • Taken for 1 to 6 months
  • May 1, 2025

Tirzepatide for Weight Loss (Obesity/Overweight) "I have had to stop. Cannot eat, close to vomiting, have lost 30 pounds. Dr. advised to stop, but I had already stopped 2 weeks ago as unable to eat. I was afraid to start the next box I had received. I am so weak I can barely walk. I do use a rollator to help me walk, but in the house I can hold onto furniture to help my balance."

5 / 10
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  • Ano...
  • Taken for 1 to 6 months
  • April 26, 2025

For Weight Loss (Obesity/Overweight) "Was doing great at 2.5 for 3 weeks, then went up to 5.0 mg for 2 weeks. Made a huge mistake of going up again to 7.5. At this doing, I had lost 6 lbs and thought it was slow results. I was vomiting nonstop for a day and a half. Could not even keep water down. I called my doctor for nausea pills. The third day I was feeling somewhat better, but still burping. I would recommend staying on the lower doses based on my experience. I have lost a total of 11 lbs after emptying my stomach. Be patient."

6 / 10
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  • Flo...
  • Taken for less than 1 month
  • December 22, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "This medicine has made me so sick. I will never take it again. I have not eaten in over five days. I am so weak, I feel like my blood sugar is low. I am not a diabetic, I only wanted to lose a few pounds. I have been sick, nauseous, vomiting, fatigue, diarrhea. Until I got everything out of my belly, my belly felt full, even when I did not eat. Constant belching. My food does not taste good. I am miserable. I’m sure it has great benefits. My other family members took it, as for me, whom is diabetic, extremely curvy, but just wanted to lose excess belly fat. I probably should’ve just gone to the gym, exercised more, or even worn a waist trainer. To me, in my opinion, it’s not worth it."

5 / 10
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  • Den...
  • Taken for less than 1 month
  • July 14, 2024

Tirzepatide for Weight Loss (Obesity/Overweight) "Works for weight loss if you can tolerate it. I went to the ER with nausea, vomiting, severe depression, and anxiety. Won't be continuing."

6 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • February 14, 2023

Tirzepatide for Type 2 Diabetes "Vomiting and rash, with severe itching. No weight loss."

1 / 10
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  • Kat...
  • Taken for 1 to 6 months
  • June 22, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "25 lbs in 60 days weight loss. Side effects minimal include vomiting and constipation. 2.4 mg for 30 days, 5 mg for 30 days. SW 175. CW 146. Height 5'0", age 41, female."

8 / 10
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  • Jew...
  • Taken for less than 1 month
  • May 30, 2023

Tirzepatide for Weight Loss (Obesity/Overweight) "It was fine for two days, but then after that, it was awful. I had vomiting, gas so bad I hurt, and weakness, and lost 10 pounds in three days. The doctor said not to take it again."

4 / 10
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  • Anonymous
  • Taken for 1 to 6 months
  • February 10, 2025

Tirzepatide for Type 2 Diabetes "Nausea and vomiting the day of and day after injection."

8 / 10
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  • dow...
  • Taken for 1 to 2 years
  • July 15, 2024

Tirzepatide for Type 2 Diabetes "Every once in a while, I get an acidic stomach and then vomit. This has only happened three times in a year."

9 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.