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Sumatriptan and Nausea: What Users Say (Page 3)

Brand names: Imitrex, Imitrex Statdose, Zembrace SymTouch, Tosymra, Onzetra Xsail, Imitrex Nasal

Reviews for Sumatriptan

Commonly mentioned side effects
  • Anonymous
  • March 29, 2010

Sumatriptan for Migraine "I had a terrible migraine on Friday and went to the doctor's office. They gave me a dose of Imitrex, and within 15 minutes, my headache was gone. It did make me feel nauseated, and my cheeks were tingling, but it was 100 times better than the headache."

10 / 10
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  • Anonymous
  • October 16, 2012

Sumatriptan for Migraine "At first, I suffered through them. This included splitting head pain, nausea, and vomiting. I started using Excedrin after a while, which helped if I took it right away. Then that started to not work so well anymore. I had one really bad one that lasted hours. I was still throwing up at 9 pm, and I was now throwing up blood. I went to the ER, and when I finally got in, they put me on an IV to hydrate me. They then added Imitrex to the bag, and I soon started feeling side effects. My head felt like I was going to pass out. My breathing became labored, and it felt like someone was sitting on my chest. They said that meant it was working. After about two minutes, everything was gone. I got pills to take at home, and they worked okay. Not as fast."

8 / 10
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  • ran...
  • Taken for 10 years or more
  • October 27, 2017

Sumatriptan for Migraine "This review is for the injectable form of Imitrex (sumatriptan) only. For anyone that has tried the pill or nasal spray forms and found them ineffective, please try the injections. They work wonders and act fast. I've tried the other types, and they actually seemed to make me more nauseous, especially the nasal spray. I keep one in my purse at all times so that I can get relief anytime a migraine hits. The pain is not bad, as the needle is very small and thin. You don't have to jab yourself, just press against your skin and push a button. The pain of a migraine is much worse! I've found the most comfortable injection site to be the bit of fat at the top of my buttocks. I use the 6mg injections, but I'm pretty sure there is also a lower dose."

9 / 10
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Frequently asked questions

  • Mac...
  • Taken for 5 to 10 years
  • June 11, 2017

Sumatriptan for Migraine "I have had great success with treating my migraines with this medication. Within 5 minutes of the injection or 10 to 20 minutes with the pill, I can feel my headache's tension, and the aura and nausea symptoms subside. For those who take pain meds or have a severe bleeding disorder caused by a defective gene in the liver, ask your doctor if this could be what's happening in your bloodstream and central nervous system from pain pills. This is not intended to treat or be a diagnosis or cure for anyone's disease, it's only intended to ask your doctor about to see if it could reduce your headache problems. This comes from a patient who is 37 years old with a severe blood clotting disorder and suffers from pain and narcotic painkiller-induced rebound headaches."

8 / 10
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  • Zac...
  • Taken for 1 to 6 months
  • March 3, 2021

For Migraine "I started sumatriptan about a month ago. My first time, the headache didn’t necessarily go away, but it stopped it from getting bigger. It also helped it last only 2 days instead of my normal 3-day migraine. The second time was actually horrible. I felt like I was drugged, dizzy, nauseous, chest pain, fingers and arms felt numb, etc. My heart was beating out of control, and it knocked me out for a good 6 hours. When I woke up, the headache was gone, but then a small one came back about 30 minutes later. So that has been my experience the last couple of times taking it. I’m extremely scared to take it on days I have work because the symptoms are super unpredictable. I’ll be trying it a couple more times, but I definitely have mixed reviews."

4 / 10
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  • Bke...
  • Taken for less than 1 month
  • June 25, 2018

For Migraine "I just took 100 mg two hours ago. The first ten minutes were fine. The next 30 minutes, I felt dazed and heavy. The next 30 minutes, I felt fine, migraine gone. But after those 30 minutes... you know the feeling you get when you laugh or smile too long and your cheeks hurt... well, that is everywhere. Just pure exhaustion with occasional pain. Stiff neck on the side I usually get migraine pain. Possible fever, lots of nausea right now. Random, but I sneezed and it killed in my neck. Glands are swollen. Throat isn’t tight, though."

5 / 10
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  • Bob...
  • Taken for 5 to 10 years
  • September 26, 2020

For Cluster Headaches "I have to take sumatriptan for my cluster headache, but wish I didn’t. The side effects are horrendous. I have to take it in bed, otherwise, I’d never be strong enough to get into bed. As soon as I take the injection, I start having chest pains and pounding on my chest. Then I get complete weakness of legs and arms and start feeling tightness in my hands. I feel like I will throw up and go all sweaty. The only thing I can do is try to sleep straight away so I sleep through the symptoms while people keep checking on me. The thing is, with all these horrendous side effects, it’s still a million times worth it to stop the pain of a cluster headache! So I have to take them. Just be very careful and make sure someone is with you when you take them. If the symptoms are too bad, go straight to the doctors or A&E."

2 / 10
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More FAQ

  • Ano...
  • Taken for less than 1 month
  • July 10, 2019

For Migraine "I started getting migraines when I went on birth control in high school, about 3-10 a year, which completely debilitated me. I’m 26 now, and despite having told past physicians that OTC meds did nothing to quell them, I was only prescribed this about a month ago. I had my first migraine since being prescribed just today, and I have to tell you I am so grateful for this medicine! Despite the directions saying to take it when you felt the headache, I went ahead and took it at the close of my aura, when I usually would take my Excedrin. After about 30 minutes, I noticed the pain was receding, but I decided to nap a little to make sure I wasn’t imagining it. I woke up after my 30-minute nap but was immediately sick and had to run to the bathroom. I normally experience severe nausea with my migraines, so I was afraid it hadn’t worked, but felt extraordinarily migraine-free. I would give it a full 10 if not for the vomiting, but that side effect is so worth it."

9 / 10
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  • Anonymous
  • December 14, 2009

Sumatriptan for Migraine "I have used Imitrex by autoinjection since it first came out. After years of migraine taking my day away, this tiny injection allows me to take it back. Unlike the other medicines, I take this at first onset, and 30-35 minutes later, continue my day on schedule. No nap, no regrets, no nausea. After the initial prescription, I met with the manufacturer's rep who helped with dosing. I was pioneering any new products when this came out. Wegmans pharmacist, my MD, and the drug rep were great help. Now, 2 shots, 1 in each leg right away. I'm 220 lbs."

10 / 10
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  • Don...
  • Taken for 2 to 5 years
  • March 21, 2023

For Cluster Headaches "I have had cluster headaches for about 10 years. The first few years, my cycles were very short, and I thought they were seasonal headaches. I was diagnosed 3 years ago with cluster headaches, and now my cycles are about 4-6 weeks of headaches, 5-6 times a week, and then I will not have another headache for a year. At the onset of a headache, I do 15 minutes of oxygen treatment. Early in my cycle, this will help keep the headaches at bay, coupled with some naproxen. Towards the middle and end of my cycle, the headaches are so severe I throw up. The burning sensation behind my eye, along with the whole right side of my face being in pain, is excruciating. I had migraines as a kid and grew out of them shortly after I turned 18. Cluster headaches are an indescribable pain. My neurologist prescribed the sumatriptan shot 3 years ago, and I have never experienced such - almost instant relief in my life. This drug is an absolute godsend."

10 / 10
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  • Anonymous
  • Taken for 6 months to 1 year
  • July 15, 2019

For Migraine "I am 25 years old and have been getting migraines since my early teens. I get 2 or 3 per month, lasting up to 3 days at a time. This is the first prescription drug I’ve tried for them, and I think the good might barely outweigh the bad. My headache is typically gone within an hour, but I experience some pretty awful side effects. My shoulders, arms, and legs get very weak (similar to flu cramps/weakness), my tongue gets very heavy and it’s hard to speak, the nausea is sometimes worse than it is when I have a migraine without medication, and I get very drowsy for a few hours after taking it. Unfortunately, when untreated, my migraines have lasted multiple days. The fact that the headache is gone so quickly is the only reason I haven’t given up on this."

5 / 10
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  • Mem...
  • Taken for less than 1 month
  • July 26, 2021

For Migraine "This is the first time I've gotten a migraine, and I contacted my doctor, and he gave me sumatriptan, the pill. It’s impossible. This pill has intensified my migraines to the point where I’m shaking, and I am so dizzy I cannot function. I am so nauseous, it’s just all bad. I just feel so dead. It’s honestly the worst experience I've ever had with a medication. Not to mention I’m so nauseated, I’ve never felt this terribly in my entire life. Never again :("

1 / 10
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  • Jus...
  • February 20, 2021

For Migraine "I took sumatriptan once last month, and it was the worst experience I’ve ever had. It did not get rid of my migraine at all, and on top of a raging migraine, I felt shaky, anxious, had chest pain, had a hard time breathing right, had tingling sensations in my fingers, felt incredibly weak, hot, nauseous, and had diarrhea. I tried to eat something to see if that would help, but I had such a hard time swallowing. It was just awful."

1 / 10
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  • TAn...
  • Taken for less than 1 month
  • November 5, 2014

For New Daily Persistent Headache "Haven't seen many people with my experience, so I appreciate Housewifeandmother's input below. Maybe my problem is also with generic sumatriptan. Maybe my dose at 100 mg is too high? But 3 out of 4 times after taking it, I became horribly nauseous and vomited the pill up within 10 minutes of taking it. I'm afraid to ever go near it again! Still looking for relief from my daily crippling headaches. Vicodin and hydrocodone seem to be the only things to relieve my pain. Started taking magnesium supplements as well, but no improvement yet. But FYI, I think my experience is uncommon."

1 / 10
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  • Kat...
  • Taken for less than 1 month
  • January 23, 2022

For Migraine "Definitely use this drug with caution. If you are someone who tends to have sensitivities to drugs and often experiences side effects from things, be wary of this one. My side effects were much worse than the headache itself. I had horrible muscle aches in my neck and head for 2 hours and then threw up violently even though the headache was gone. Please ask your doctor about alternative options to this."

3 / 10
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  • fra...
  • Taken for 2 to 5 years
  • March 22, 2016

Sumatriptan for Migraine "I have had migraines since the age of 6, I have tried everything. I unfortunately need pain medication about 10% of the time. I sure wish I would have had these injections years ago. They work most of the time. I have very severe pain and nausea, and it does help."

6 / 10
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  • sti...
  • Taken for 1 to 6 months
  • September 16, 2018

For Migraine "After years of 'sick' headaches that nothing touched, my Dr. prescribed sumatriptan 100 mg. I resisted taking it until a couple of weeks ago when I finally couldn't stand my headache any longer. It made me very nauseous for about an hour, then the nausea and my headache were gone. This morning, I had to take it again. This time, I was nauseous for about 1 1/2 hours, and my whole face was sore. I don't know if it is worth it, even if it does get rid of the migraine."

8 / 10
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  • Ohi...
  • Taken for 10 years or more
  • May 25, 2017

For Migraine "This was hugely helpful for me when my doctor figured out that I was suffering from migraines. Once in a while, I get sick to my stomach before the medication takes effect (especially if I've delayed taking it, for whatever reason), but I can't describe how much better it is to have this than to suffer. If I lose a dose to emesis, I'll take another with a small amount of water and wait for everything to calm down. Keeps me functional, where before I'd have been wiped out and wishing for death for a day or more. Side effects for me have been very mild and occasional. Slight tingly feelings, or a little bit of mental 'distance' from my surroundings. Words can't describe how much better this is than torture."

8 / 10
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  • Mix...
  • July 14, 2016

For Migraine "I'd taken Excedrin for years with some effectiveness and then had a streak where headaches would return within a day and sought medical attention. An urgent care doctor prescribed Bubalbital-APAP-Caffeine and I used it as needed for about a year and was happy with the results, but the prescription was running out. Because the medication was prescribed by an urgent care doctor, the prescription couldn't be refilled, so I had to see an internal medicine doctor and he prescribed Sumatriptan. After taking the medicine today, it did eventually take away my visual auras and it seems to block the full-on migraine, but I feel kind of crummy with sinus drainage and pressure, grogginess, and slight nausea. Going to try with pain reliever Naproxen."

5 / 10
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  • Anonymous
  • March 3, 2011

Sumatriptan for Migraine "I've never felt so sick in my life. My blood pressure shot up to the upper 100s, and I felt like I was going to pass out."

3 / 10
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  • MW7...
  • Taken for 1 to 6 months
  • November 29, 2022

Sumatriptan for Migraine "Not a drug for everyone. It made me feel hung over and sick to my stomach, and my headache came right back, not long-lasting."

1 / 10
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  • Anonymous
  • March 14, 2017

For Cyclic Vomiting Syndrome "It is fairly effective if taken in time. Usually with a nausea medication too. Doesn't fully resolve symptoms, but takes the edge off and helps with vomiting. It is also very expensive medication."

8 / 10
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  • cry...
  • October 16, 2009

Sumatriptan for Migraine "Imitrex helped with my migraines but made me nauseous."

3 / 10
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  • Anonymous
  • July 7, 2010

Sumatriptan for Migraine "The 1st dose made me so nauseous, and I fell asleep for 1.5 hours and awoke still nauseous and with a headache. I then took a second pill, and then I was perfect within 30 minutes."

5 / 10
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Reviews may be edited to correct grammar/spelling or remove inappropriate content. Reviews appearing to come from parties with a vested interest are not published. This information is not intended to endorse any medication and should not replace the expertise and judgment of healthcare professionals.