Pemazyre for Cholangiocarcinoma User Reviews
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"My husband has completed 3 rounds of 13.5 mg Pemazyre. He has had a problem with ascites in his abdomen and has been receiving paracentesis 2x per week. Originally, he had been averaging 8-10 liters each time during chemotherapy. He completed 6 rounds that failed to help him. He started the Pemazyre, and the yield of the paracentesis dropped steadily to 4-6 liters. An encouraging sign!!! He has had a number of side effects: hair loss, taste loss, ache in his jaw, pain in his limb muscles. During the second week of his 3rd round, a bruise on his calf began to look like blood under the skin and continued to spread, causing great pain and eventual hospitalization. Apparently, this is a rare and serious side effect and may involve calcium blocking blood vessels and flow. At that same time, a nearly 100% loss of vision has occurred - blind!!! A corner of the retina has lifted, and we pray it goes back into place to return his eyesight. Doubtful my husband will continue a low dose."