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User Reviews for Naloxone / pentazocine

Naloxone / pentazocine has an average rating of 7.1 out of 10 from a total of 24 ratings on Drugs.com. 67% of reviewers reported a positive effect, while 24% reported a negative effect.

Condition Avg. Rating Reviews Compare
Pain  
7.0
15 reviews 1126 medications
Chronic Pain  
7.4
9 reviews 110 medications
Summary of Naloxone / pentazocine reviews 7.1 24 reviews

Reviews may be edited to correct grammar/spelling, or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published.

Reviews for Naloxone / pentazocine

Anonymous August 29, 2010

Talwin Nx (naloxone / pentazocine) for Pain: “I deal with chronic back and leg pain due to a ruptured disc and bulging disc above and below, 3 ruptured discs that were fused via surgery. I have been on opiates (hydrocodone, morphine, oxycet) for 4 years and finally got sick of the side effects and physical dependency these drugs create. The dependency and withdrawal finally got worse than the pain that these drugs released. I detoxed cold turkey off of them for 2 weeks and then decided to try this medicine. I have been on it for about a month and it has worked wonders. Very few side effects and sweet pain relief. I do not have to be on this medicine every waking moment and I can even go days without needing any. So far this has become the answer I have been searching for.”

9 / 10
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icybluiz July 20, 2010

Talwin Nx (naloxone / pentazocine) for Pain: “I have been taking Talwin NX for about 3 years now. I have two fractures in my mid and lower back. The first Doctor I saw for this condition had me on Vicodin 10mg. He had me on 56 pills a week. After awhile, my weekly appointments stopped being about pain and started to be about getting that script filled. I finally woke up to the fact that I was addicted to these pills. It really scared me. I went to my primary physician and he really helped me. He used Talwin to detox me off of the Vicodin. It proved to be an excellent pain medicine for me. I don't know if it's my constitution but I am not addicted to Talwin NX. If I run out and can't get to my Doctor or whatever, I do not experience any withdrawal symptoms.”

8 / 10
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billval March 5, 2008

Talwin Nx (naloxone / pentazocine) for Pain: “Stronger pain med, is schedule 3 drug, so its not as hard to get a prescription for. I take it for severe back arthritus pain, and it works wonders. Not as hard on the liver as drugs containing tylenol. Stay away from tylenol if you have liver disease.”

7 / 10
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Joey hurts-a-lot · Taken for 1 to 2 years March 26, 2020

Talwin Nx (naloxone / pentazocine) for Chronic Pain: “Complete joke! I’ve had 9 different back surgeries and I was in horrific pain the entire time. I thought very seriously about suicide to relieve the unbearable pain. I finally retained an attorney and sued the pain management doctor. The judge said his treatment amounted to sadistic torture. I won my case and was able to hire a compassionate doctor. Talwin made me feel severely anxious and sick the entire time that I took it. I would never take it again.”

1 / 10
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Shy-D December 22, 2013

Talwin Nx (naloxone / pentazocine) for Chronic Pain: “Talwin was first given to me when I had wrist surgery to reattach tendons and ligaments torn from the bone during a car accident. Plus I have fibromyalgia and psoriatic arthritis. And I'm allergic to all the morphine, codeine types. My wrist surgeon coupled Talwin NX with Phenergan and it worked like a charm. Now I use that very combination for psoriatic arthritis flares. It's wonderful!”

10 / 10
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mizzmoze · Taken for 5 to 10 years January 21, 2014

Talwin Nx (naloxone / pentazocine) for Chronic Pain: “Great medicine for controlling pain/chronic pain. non addictive.the nclenal stands for Nicene which is arcane.an opioid & drug overdose reversal medication. it works by blocking opioid and other addictive medications from building up in cells/body. as talwin contains small amounts of opioid the amazing thing about this medication is while using for chronic pain, it took away all mental urges or desires to think about drinking alcohol.which I had stopped yrs before but had that mental desires or thoughts too drink.Cravings so to say.it may have same long term result for addicts who crave other drugs..amazing! An important fact that is not a warning from drug co.is .it blocks relax meds before procedures su.colonoscopy, relax medication.scary”

10 / 10
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Anonymous · Taken for less than 1 month May 29, 2012

Talwin Nx (naloxone / pentazocine) for Pain: “Hydrocodone wasn't providing relief through the entire duration between doses and doctor wouldn't prescribe more frequently because of my "body size". Oxycodone didn't touch the pain, so doctor prescribed Talwin NX. I developed severe hives by the second dose and developed breathing problems. Didn't take a third dose and it didn't help with my pain that much. Have sacroiliac joint dysfunction with severe pain and lumbar pain with cycling muscle spasms. Am allergic to steroid so trigger point injections didn't work either.”

2 / 10
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Anonymous April 24, 2010

For Pain: “I have a congenital birth defect called Arnold-Chirari Malformation. Part of my brain sticks out the back of my skull and pushes against my spinal cord. I live in a small town and had a difficult time getting my pain managed because I was in my late 20s and was told I couldn't receive pain pills until I was older. (Backwards and shameful, I know.) I resisted attempts to make me submit to brain surgery because I have Factor V and a history of DVT and PE. After spending nearly 3 years of my life bedridden with severe pain in my head, eye, neck, and spine, unable to work or study, a physician finally gave me this medication. It gave me my life back and nobody questions the fact that I am young and seeking only pain relief in order to function.”

9 / 10
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5string January 15, 2014

For Chronic Pain: “I have been taking this med for many years and it still works great. It has greatly improved my quality of life. I have had several cervical neck surgeries and I have lived with chronic pain for many years. This medication has been a life saver for me and I would recommend it to anyone living with chronic pain. Thank You”

9 / 10
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justin82 March 15, 2008

For Pain: “I am prescribed to Talwin NX for chronic left leg pain due to having numerous strokes, seizures, and two heart-attacks. I have also been diagnosed with Crohn's disease. I think this medication works very well and when I don't take it for awhile I have no adverse reactions-(withdrawals).I have also not formed a dependency to this medication unlike other narcotic pain medications I have been prescribed.”

9 / 10
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parsec October 4, 2011

For Pain: “I take the generic form (PENTAZOCINE-NALOXONE TABLET). I have Fibromyalgia. I moved to GA around 3 yrs ago and luckily my last Pain Management Physician was able to refer me to a Doctor in a nearby town. I travel 132 miles round trip to him monthly. At the point of seeing him I was in real bad pain and he prescribed naloxone/pentazocaine generic. This medication has helped me I take a steady 1 to 2 every 4 hours. It is more rare now to take 2. I know it is masking the pain and it does not mess with my head. I can get into major pain at times. It passes, I think easier because I have a steady level in my system.”

10 / 10
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Marines4Jesus March 31, 2018

Talwin Nx (naloxone / pentazocine) for Pain: “During an armed robbery, I was shot 3 times, a month in coma, major open abdominal exploratory surgeries to repair damage & stem the lose of blood, leaving large wounds & 150+ stitches/staples & ribs wired back together, bullet frags in my spine & nerve damage. But I was alive, & could barely walk, but the Talwin nx was a tremendous help to allow me to ease the pain, so I could function & so minimal tasks through the day. It did such a good job at blocking the pain, that I had to use discretion after I took it, not to over do it, as I might & bust open any stitches, though I felt little discomfort at the time. My doctor prescribed them with no issues for about a year, and as I healed more , my frequency between doses of all my meds, including the Talwin lengthened, initially I would take 1 every 4-6 hours as prescribed, then I got to where maybe 1 a day would get me through the day... but after that and without access to pain meds, The quality of life was lessened”

9 / 10
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Anonymous May 3, 2011

For Pain: “I was prescribed this medicine after having one of my lower large molars pulled. I ended up with a dry socket and in horrible pain. This is a great pain reliever without the side effects like the others. I will use it again if needed.”

7 / 10
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Worker July 8, 2019

Talwin Nx (naloxone / pentazocine) for Chronic Pain: “I had a head on collision with my car and another vehicle in 1996. My neck, shoulder, and back were affected. Initially put in Loritab but I was nauseated and also worried about becoming dependent. I then tried the injections in my back and did pain management. My job was physically demanding and it was difficult to just walk. My doctor prescribed me Talwin NX about 10 years ago. Initially my pharmacist told me that it was an older pain medication and that I needed my doctor to change me over to Loritab or something else. I told the pharmacist my concerns about opioids and he has started keeping the Talwin Nx to fill my prescriptions. I only take them when I need to be very active. Thirty pills usually last me 45-60 days as the most I have taken in a day is 1 pill. I have gone without taking any for over a week. I have been injured multiple times since that car wreck but will only take Talwin for my pain.”

10 / 10
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animalfan · Taken for 5 to 10 years June 21, 2016

Talwin Nx (naloxone / pentazocine) for Chronic Pain: “I was on this for most of the 80's and 90's. No need to up dosage, I would give anything to get them again. Last year I weaned off morphine, because it was too low of a dose. 60mgs. Per day! I moved, and back home I got up to 120mgs of methadone per day. Plus pain Doc'S are VERY scarce here, the few there are either won't take new patients and/or my insurance. So to answer the question- TalwinNX works really well on pain. It can cause anxiety in some people.”

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menengitus man11 March 10, 2017

Talwin Nx (naloxone / pentazocine) for Pain: “worked like a charm for pain and anxiety for migraines you have to start slow and get used to it after that its better than mothers milk and a safe alternative to oxys opama ext old school drug when people were responsible and didn't need so much control,,,,,do they still make it in the old form ,,,don't drive tho remember”

8 / 10
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Jon December 11, 2019

For Chronic Pain: “I was first prescribed Talwin (pentazocine) after I became allergic to Hydrocodone and Oxycodone. I did develop a tolerance to both those drugs and had up up my dosage. My orthopedic doctor wanted me to try Talwin. He said it was an old school pain reliever. I started out on 2 every four hours. After being on it for five years now, I take three every four hours. It just flat takes away the pain without getting high. I have no plans on going to a higher dose. If I forget and take too much I either start itching or throwing up. It works just as well today as it did when I was first prescribed it. I think those who are in need of real pain relief that don’t like the effects of Hydrocodone or Oxycodone Should give Talwin a try. It just flat works for my type if pain. Which is osteoarthritis in my hands, back, neck.”

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elainesul1 October 28, 2008

Talwin Nx (naloxone / pentazocine) for Pain: “TALWIN NX is the only drug which relieved the pain in my upper spine. I have been taking two a day for 12 years and have not needed to increase dosage. To me it was a miracle drug.”

10 / 10
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LadyJoon October 12, 2007

Talwin Nx (naloxone / pentazocine) for Pain: “this medication was prescribed for constant back pain. While taking Talwin NX, I was mean, irritable, and had the shakes. ”

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Anonymous February 9, 2011

Talwin Nx (naloxone / pentazocine) for Pain: “Worked great for my back pain”

8 / 10
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Anonymous December 6, 2009

Talwin Nx (naloxone / pentazocine) for Pain: “Was given this for pain, had bad shaking, very anxious and irratable. Also dizzy and nauseated.”

1 / 10
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Roger Dodger January 8, 2014

For Chronic Pain: “I've been on this medicine for five years and is the best pain relief for my knees and back. Still can't do much on this medicine but it takes away the pain. Lay down after taking for best results.”

10 / 10
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Tango4 March 27, 2017

Talwin Nx (naloxone / pentazocine) for Chronic Pain: “Used Talwin NX for Carpel Tunnel. Worst feeling ever! I felt drunk, for car sick, had horrible dreams- it did not help with pain relief. I would not take it again!”

2 / 10
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Anonymous · Taken for less than 1 month July 20, 2012

Talwin Nx (naloxone / pentazocine) for Pain: “Acute allergic reaction. ER treatment of Epipen and Steroid injections and 5 day regimen of prednisone.”

1 / 10
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This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge and judgement of healthcare professionals.