Molnupiravir and Diarrhea: What Users Say

• ali...
• Taken for less than 1 month
• March 29, 2023

Molnupiravir for COVID-19 "Just finished 5 days of Lagevrio taken one day after testing positive for COVID. 70-year-old female, with no other health issues. The antiviral began its work after 1 day, with no more pain in the throat or headache, and heavy mucous production stopped. However, it has caused diarrhea and turbulent growling in the intestines and stomach for the last 4 days. No appetite, and only ate two muffins with little butter every day with weak tea or plain water. Kept up fluids as best I could. Little sleep at night and had to rest all 4 days, doing anything has been almost impossible. I read that once the medication is over, these symptoms will disappear, so I am looking forward to tomorrow."

• Cov...
• November 9, 2022

For COVID-19 "Began taking Lagevrio 200 mg the Monday I tested positive. After 3 doses (12 pills), I informed my healthcare provider that I stopped taking it. I developed an odd pulling pain on the left side of my stomach, and the diarrhea has been horrendous! No metallic taste, but I have been experiencing random metallic smells. Whether it has actually helped with my symptoms is a complete mystery, as I was 2 1/2-3 days into symptoms before I began taking it."

• Moo...
• Taken for less than 1 month
• March 26, 2023

For COVID-19 "This stuff is awful! I am immunosuppressed, so I decided to take it even though my COVID symptoms had improved on day 3. I woke up with a completely different set of symptoms: a feeling of general malaise, lightheadedness, diarrhea, and unable to eat. A horrible metallic taste which is constant. Still in bed on day 6 with no signs of improvement."

• M L...
• Taken for less than 1 month
• April 17, 2023

For COVID-19 "I am 71.5 with heart disease, started this mRNA drug on day two of COVID symptoms. I took this for 2 and a half days and developed red skin, a stinging rash, and diarrhea. Stopped and hoping COVID doesn't return."

• Goo...
• Taken for less than 1 month
• September 7, 2024

For COVID-19 "I’m a 50-year-old woman with POTS, EDS, and mast cell disorder. I got this med one day after I tested positive for COVID-19 (my second round). I started feeling better by the next day. I’ve had some minor side effects: diarrhea, headache, and sleepiness. I’ve actually slept better than I ever do, and my mental state is very positive. I’m on day 5 and have no COVID symptoms, I would take it again. No issues with mast cell reactions either."

• LUA...
• March 13, 2023

For COVID-19 "Tested positive and called a health care professional. Recommended molnupiravir, and I started taking it on the second day in the evening (4 capsules every 12 hours for 5 days). I was very stuffed up and had a low-grade fever, which went away after the second day. Sinus drainage and headache are very persistent. Currently have laryngitis. Cough is not productive, and headache remains. Did have a skin rash for two days. Took Benadryl. Another review mentioned nightmares, I have experienced very vivid dreams. Overall, I feel tired most of the time. Appetite is minimal, and I have no sense of smell or taste and have had diarrhea off and on since the third day of medication start. Cough is very persistent, and so is sinus drainage."

• LJM...
• Taken for less than 1 month
• September 5, 2024

Molnupiravir for COVID-19 "Lagevrio worked well and kept me from experiencing any severe symptoms of COVID. It's critically important that you obtain this drug the moment you know that you have COVID. The earlier in your illness that you take this drug, the more effective it will be. I was on Lagevrio for 5 days. The only noticeable side effect was some diarrhea. If you're on antipsychotic medication(s), your doctor will give you this drug instead of Paxlovid due to interactions. Please note that most insurance plans do not cover Lagevrio, you will need to go on Lagevrio's website and get the low-cost coupon for it. Have lots of water on hand since you have to take 4 of these pills every 12 hours."