Medroxyprogesterone and Mood Swings: What Users Say (Page 2)

• Wor...
• January 29, 2020

Medroxyprogesterone for Abnormal Uterine Bleeding "I cannot stress enough about how bad the Depo is! I got the shot in Sept. 2019 and am still having horrible side effects. I am so bloated, sore breasts, and having intense cramping. I've been bleeding non-stop for almost 5 months now. This is so depressing! Along with that, I am having extreme mood swings and depression. I never had either of those things before. I wish I could go back in time and never get this shot ever. I only had one shot, I had no idea these horrible side effects would last so long."

• tnk...
• November 30, 2014

Medroxyprogesterone for Birth Control "I got this shot a few weeks ago, and my side effects are already horrible. I had anxiety before, but now it's so much worse. My mood swings are unreal, and my breasts have been so tender to the point where I can't touch them at all, and they've grown a ton. Not to mention the few pounds I've already put on in the short time. I will never take the shot again. I don't recommend this form at all. Once you get the shot, no matter how miserable the effects are, you can't do anything about it. Going back onto the pill once this wears off."

• Hig...
• Taken for 1 to 6 months
• March 11, 2015

Medroxyprogesterone for Birth Control "I am 21 years old, was placed on this medicine for having high blood pressure and it being an estrogen-free birth control. I was terrified of weight gain, spotting, and mood swings, all of which this shot is rumored to do. I have experienced absolutely no bleeding since my first shot, got the second shot today, and no weight gain (I do exercise daily). I have been somewhat emotional around the time of my normal period, but no more than usual. Overall, I love the shot, and having no period is a plus all around!"

• Hig...
• Taken for 1 to 6 months
• March 11, 2015

Medroxyprogesterone for Birth Control "I am 21 years old, was placed on this medicine for having high blood pressure and it being an estrogen-free birth control. I was terrified of weight gain, spotting, and mood swings, all of which this shot is rumored to do. I have experienced absolutely no bleeding since my first shot, got the second shot today, and no weight gain (I do exercise daily). I have been somewhat emotional around the time of my normal period, but no more than usual. Overall, I love the shot, and having no period is a plus all around!"

• kmc...
• October 29, 2009

Medroxyprogesterone for Birth Control "I am 29 years old, and I have had 3 jabs of the depo in the last year and a bit. MY PROS: No period pain every month. No babies (three is enough for us). No worries about tampons, etc. My CONS: headaches a lot, mood swings - I am a little depressed and snappy at the kids. I don't want to get intimate with my poor husband at all, and my face is covered in acne (not really, but for me, YES). I have gained weight!! (5 kg). I was supposed to have my next jab in June this year, and I didn't go for it, and I still don't have my period 5 months later!!! I think for me personally, it is no good."

• Man...
• Taken for 6 months to 1 year
• June 27, 2015

Medroxyprogesterone for Birth Control "I would recommend this to everyone. My experience on the shot has been great. This is about my 9th month now, and I never had to deal with any crazy side effects like weight gain, acne, etc. However, in the first 3 months, I did have mood swings, but they were never worse than any normal mood swings (for example, period mood swings). I never got my period, bleeding, or any spotting until 6 months after I started the shot! And even then, my period was very light and quick. Be sure to drink a lot of milk or eat dairy to replace the calcium that gets stripped from your body by taking the shot. If you don't replace your calcium, your bones can become weak or you can experience more side effects. Just take care of yourself :)"

• jez...
• Taken for 1 to 6 months
• January 13, 2015

Medroxyprogesterone for Birth Control "I am 28 years old, I have been on the Depo shot for 3 months now to regulate my periods. My first 2 months, I didn't get my period at all, no side effects except a headache for the first week. Now into my 3rd month, and I have had my period for going on 3 weeks straight, and it's really stressing me out. I have been irritable these past weeks, major mood swings, and lost my sex drive. And no changes in my weight, but pretty sure I will not continue this method of birth control."

• Rac...
• August 7, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "I found this site and comments of great interest. My daughter had a shot earlier this year and complained of continuous bleeding (not spotting), feeling bloated, nausea, headaches, cramps, and very depressed and emotional. She went to another doctor who has put her on antidepressants and pills to supposedly stop the bleeding, a week on, still bleeding. My daughter is 24 and has changed from a lovely, bubbly, happy person into an ill zombie who sits on the sofa all day, fatigued and in pain. I certainly intend to seek legal advice."

• Fig...
• Taken for 1 to 6 months
• August 4, 2016

Medroxyprogesterone for Abnormal Uterine Bleeding "I had the shot on March 20, 2016. I had 2 weeks before the bleeding started. At first, it was spotting, but every day. Then it was heavier bleeding. Then it got so heavy I was changing an ultra tampon every 45 minutes to 2 hours, even at night. I was at my doctor's, exhausted from lack of sleep, crying, anemic, with hormonal acne, horrible back pain from constant period pain, and terrible mood swings. I only had the 1 shot. I refused any more. It's currently August, and I am still bleeding. There is no sign of it ending! I would not have this shot again, even if they paid me!"

• Anonymous
• Taken for 1 to 6 months
• June 8, 2015

Medroxyprogesterone for Abnormal Uterine Bleeding "Absolutely the worst decision I have ever made! Got the shot on March 13 to straighten out my hormones. Was on my period when I got the shot. Stopped a week later. April 4th, I started again. It is now June 8, and I have not stopped! Plus, I am crankier than before and VERY emotional! I am due for my second shot, and I refuse to get it! This is absolutely ridiculous!"

• Wha...
• Taken for 1 to 2 years
• April 19, 2017

Medroxyprogesterone for Birth Control "On Depo for 19 months, began taking it after my second child. Had no period. Major mood swings, constant exhaustion, and trouble sleeping. No sex drive - after some research, I discovered why. Depo is used as a chemical castration drug for sex offenders in multiple states. My doctor did not mention that I was drugging myself like a convicted sex offender, did yours?"

• Nat...
• Taken for 1 to 6 months
• October 8, 2013

Medroxyprogesterone for Birth Control "My first shot of Depo-Provera was almost three months ago, and I am due for my second shot in less than two weeks. I will not get that second shot and must say Depo-Provera worked very badly for me. I've been bleeding straight for two months now, awful mood swings and depression, extensive hair loss, and no sex drive at all."

• ann...
• July 25, 2012

Medroxyprogesterone for Endometriosis "It has been almost 6 months since my shot, and I have been on my period the whole time. I gained 45 pounds, and I was the most depressed I've ever been. I went insane with mood swings, my already bad pain got worse, and I had head-splitting migraines, among other things. I don't recommend it to anyone. It should come with a prescription for Xanax and some weight loss pills to try to stay on top of things."

• Mar...
• Taken for 1 to 6 months
• July 15, 2019

For Amenorrhea "So I was originally prescribed Provera about a month ago. I took the 10 mg once a day for 10 days and was told to wait a week for a period. A week went by and nothing. I called the doctor and she prescribed me a “stronger” dose, which was 10 mg twice a day for 7 days. And I waited another week. I still haven’t had a period. I have PCOS and have been trying to get pregnant. I also had irregular periods and this past year haven’t had a period. I’ve experienced bad mood swings that have been tough for my husband and me. I have to call my doctor in the morning and see what my next steps are. Has anyone else experienced this? And what did you have to do after?"

• Ska...
• Taken for 1 to 6 months
• March 13, 2016

Medroxyprogesterone for Abnormal Uterine Bleeding "I had my first Depo shot November 25, 2015. I was good for a week with no bleeding. I was supposed to go get my second shot February 25, 2016, but decided not to as I bled and still am bleeding today, 03/13/2016. Cramps are really bad, clots are bad. I wish I had never had this shot. The doctor doesn't tell you that this could happen for months on end. If they did, I guess most of us would have thought twice about having it. I am full of regrets, and I'm more depressed than I was before. I hate the bleeding, it makes me feel disgusting and dirty as it's never-ending on a daily basis. My mood swings are at what I would call a dangerous level. I would suggest that women thinking this is the best contraceptive out there to think twice and read what has happened to us."

• Bec...
• August 29, 2014

Medroxyprogesterone for Birth Control "I started the shot when I was 17, about to be 18. I am now 20, about to be 21. Very effective at preventing pregnancy. However, I have terrible mood swings, migraines, and weight gain. When I started taking Depo, I was the healthiest I have ever been. Slowly but surely, I put on the pounds and my depression became unbearable! The first year, I didn't gain much, maybe ten pounds, and went from a size 4 to a size 6. I weighed 135, now I weigh about 170. It's horrendous! I just switched birth control yesterday, so I hope it treats me better than Depo Provera!"

• lea...
• Taken for 1 to 6 months
• May 18, 2016

Medroxyprogesterone for Abnormal Uterine Bleeding "I got the Depo shot a month ago, and it's been the worst experience of my life! I haven't stopped bleeding, I have horrible mood swings, I'm always depressed, I'm losing weight, and it's basically ruining my life. I hate this shot, its side effects are horrible. I do not recommend it at all!"

• JD3...
• Taken for 1 to 6 months
• May 31, 2023

Medroxyprogesterone for Birth Control "I am month 2 on Depo, and I would rate it a zero if I could. Since receiving the injection, I have suffered migraines and/or headaches daily. I'm so exhausted I can't make a day without a nap, mood swings daily, a loss of interest as I have no energy, feeling unwell all the time, hot flashes galore, been on my period for a month, and it's major cramps. I wish I would have read about the side effects. I will never get another one and keep telling my husband I regret it daily. I just want my life back, I was hoping it would help with my periods, that is why I was prescribed it, and it backfired. Yuck."

• Bet...
• Taken for 6 months to 1 year
• November 11, 2019

Medroxyprogesterone for Birth Control "Depo-Provera made my periods stop after about 7 months (amazing). It gave me relief from chronic migraines I've had for years. I only have occasional cramping now and have not gained weight. HOWEVER, the first two injections sent my moods wild. I was often extremely anxious and sad (this did go away!). I am doing great now and most importantly, I am not pregnant."

• Kok...
• April 24, 2013

Medroxyprogesterone for Birth Control "I am 21, and since I first received the shot in January, I have been bleeding ever since. Sometimes light, sometimes like an actual period, with cramps and migraines. Also, this medicine has completely jacked up my hormones. I am angry ALL the time, ALWAYS sad. I cry every day, over the smallest issues, or for no reason. I am happy, and in a split second, I will feel very low or even have suicidal thoughts. I experience extreme mood swings and flip out on my boyfriend-coupled with less sex from the bleeding. It's very frustrating. I am hoping that this is just my body still adjusting to the medicine. I haven't had any weight gain or acne though (knock on wood)."

• Mae...
• Taken for 1 to 6 months
• October 17, 2019

Medroxyprogesterone for Abnormal Uterine Bleeding "Got the shot in June before my period. I have been spot bleeding since! I thought my period was gonna stop, at least I thought it’s now October... Mood swings, yes... depression, less active than normal. I have barely got appetite, can’t sleep. Something changed in the depo, never had this happen. Very concerned for myself and others."

• Leg...
• June 26, 2016

Medroxyprogesterone for Abnormal Uterine Bleeding "I got this April 2016 and have experienced extreme depression, rapid weight gain, irregular bleeding for weeks, acne, increased breast size, decreased sex drive, and horrible mood swings. This has been the worst time of my life."

• Sar...
• Taken for less than 1 month
• May 27, 2021

For Amenorrhea "I was prescribed a 10 mg dose of medroxyprogesterone for 10 days to start my cycle as we try to conceive. The 10 days were kind of weird - lots of mood swings, cramps, and headaches. By day 4, it seemed to normalize, but then it did seem to make me feel lousy days 6-8ish again. I think by the end I had just gotten used to it. I woke up with my period on day 3 of not taking it. I will say, this is one of the worst periods I have ever had (remaining positive as I’m hopeful we will conceive this cycle!). Cramps are really bad, and the flow is the heaviest it has been in years. Just a heads up!"

• Anonymous
• October 20, 2011

Medroxyprogesterone for Birth Control "I've been on the Depo shot for a year and a half now, and I have been bleeding ever since I took it. I have experienced a lot of weight gain and depression and tons of mood swings. You get cramps every day as if you just got your period. I wouldn't recommend it if you don't like bleeding. Might work for some people, but not for me."

• Anonymous
• Taken for 1 to 6 months
• June 24, 2022

Medroxyprogesterone for Birth Control "The absolute worst thing I have EVER tried in my life. It has made my life a living hell for the past 6.5 months, and I still live in hell. I have gotten 2 shots of Depo and refused to go for the 3rd shot, which was due a little over 2 weeks ago. I have gained 20 lbs so far, and it’s gotten even worse since I stopped the shot 2 weeks ago. Depression, acne, and mood swings are horrible, but the worst of all was the constant heavy bleeding for 5 months EVERY SINGLE DAY! I became severely anemic that I could barely walk for 10 minutes due to extreme fatigue and exhaustion. No sex drive and no desire to do anything at all! Just sleeping half of the day and feeling tired without doing anything. This shot has been the worst nightmare for me. I wish I had done my research before getting it. I now regret it 200%."