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Lamotrigine for Anxiety User Reviews (Page 2)

Brand names: Lamictal, Lamictal XR, Subvenite, Lamictal ODT, Lamictal CD

Lamotrigine has an average rating of 7.1 out of 10 from a total of 111 reviews for the off-label treatment of Anxiety. 64% of reviewers reported a positive experience, while 23% reported a negative experience.

Reviews for Lamotrigine

  • Root...
  • Taken for 1 to 6 months
  • June 19, 2015

"No side effects. I've been suffering from depression and anxiety since I was a teenager, it had help so much. I am so thankful for this medicine it saved my life, I would suffer for days with no sleep. anxiety is a killer I am glad this med is on the market. I would have committed suicide because of the anxiety, I give many thanks to my doctor for finding something that helped, I can live my life finally."

10 / 10
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116 Report
  • TheAn...
  • Taken for less than 1 month
  • June 27, 2016

"I've had a seizure disorder for 10 years but hadn't had a tonic-clonic in about 6 years, so I've been off Lyrica for a year. I have GAD, PTSD & minor depression-but the massive anxiety nearly killed me, I had become borderline agoraphobic, could not slow my heart down, lost 90lbs in 2 yrs-really thought I was dying & actually reached the point of being ok with death as long as the anxiety stopped. I've been on benzos for years, but need to get off. I was admitted to the hospital for chest pains and mid Ativan push, had a t-c seizure. Enter Lamictal. Today is day one. My heart rate is normal. The bald eagles/vultures in my stomach (not butterflies) are gone. I feel more relaxed than I can ever remember. Fearless. Thank God."

10 / 10
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89 Report
  • Anonymous
  • Taken for less than 1 month
  • May 11, 2020

"My anxiety is severe where I experience nerve pain. I was prescribed to the medication lamotrigine from my psychiatrist 2 months ago but, I was scared to take it. I recently got over the fear of taking this medication and started it 8 days ago - I feel no difference, just feel more anxious and jittery. No problems in sleep but, I would wake up feeling super jittery from chest to legs. Will continue to take it and see how it goes in the next few weeks"

4 / 10
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53 Report

Frequently asked questions

  • 64tet...
  • November 7, 2022

"Amazing improvement in anxiety after years of trying other meds. I have been through a pharmacopeia of meds to learn that I have been treating the symptoms rather the source of my problems. I can only share with everyone my issues and maybe this will help someone but I am no doctor. I have had anxiety issues for years and have been managing with benzos until the Dr's decided benzos we're bad and forced everybody off of them regardless of the devastating withdrawal and the return of anxiety. I suspected a malfunction of my HPA axis. What had been eluding me and my doctor was the presence of too much glutamate. I learned that glutamate is the most prevalent excitatory neuro transmitter in our bodies. I also learned that this excessive glutamate was causing excitotoxicity effectively destroying the neurons causing not only anxiety but a host of other issues along with it. The lamotragine inhibited the release of glutamate which alleviated the debilitating anxiety I had for years."

10 / 10
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25 Report
  • ABano
  • Taken for 6 months to 1 year
  • June 27, 2017

"I've had debilitating anxiety and depression most of my life and going into perimenopause made it a thousand times worse. I was on Seroquel and Lexapro, but my mood swings, depression, extreme fear, panic attacks and anxiety was still absolutely paralyzing. I also developed intrusive thoughts. My doctor started me on Buspar, Bio-Identical Hormone therapy and Lamictil. It changed my life. I have had no serious side effects other than mild memory impairment at first. I control the Lamictil rash on my face with 5% Benzoyl Peroxide Cream and Hydrocortisone cream. Prayer, faith in God and coping mechanisms have also helped me tremendously. My mind is clear and I feel normal. Give it a shot!"

10 / 10
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Are you taking this medicine?

  • Volanis
  • June 1, 2017

"I have had anxiety and bouts of depression my whole life. I've tried ADHD meds, anxiety and SSRI's and have self medicated too for years. My wife, a therapist, has been telling me I've bipolar 2 for years. We'll, recently I've been having anxiety and near panic attacks every day. So I started taken lamotragine 2x25 a day and after 3 days my panic went away and my racing thoughts and depression too. I never thought a drug could work this well but it's been amazing I really can't believe it"

10 / 10
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  • btm
  • Taken for 6 months to 1 year
  • October 23, 2018

"I have been taking 100mg lamotrigine twice daily for several months now and feel really good on it. The only reason I gave it a 9 out of 10 is because I still struggle with mood issues with PMS. I first started titrate 25mg 2xd and bumped up to 50mg 2xd. I felt like I was getting too anxious and dropped back to 25mg 2xd. After my anxiety was under control, I began to titrate back up and things went really well. I actually think I was getting more anxious before because I was so used to feeling anxious, and not feeling anxious was so foreign to me. Anyway, I'm glad I tried it and I'm glad I'm on it!"

9 / 10
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  • Ansioso
  • March 3, 2017

"I suffered for 39 years of chronic anxiety. I've taken many meds (SSRIs, benzos) CBT, meditation, etc. They helped to certain extend but the crippling anxiety was always there, waiting for me every morning. Anxiety affected everything in my life, the job I did, the women I dated, the manner I interacted with others and many other aspects of my life. Then I tried Lamotrigine and once I reached 100 mg I felt normal for first time in my life. This is a miracle drug. I'm currently taking 300 mg.I had a had a rash when I was in 100 mg. Many people overreact and stop taking it thinking there skin is going to fell off. I just went back to 75 mg for few more weeks and slowly increased the dose without any issues. 99.9 of the rash is innocuous"

10 / 10
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70 Report
  • Edano
  • Taken for 5 to 10 years
  • September 28, 2018

"Bi Polar II: Lamictal, it has given me a balanced and more meaningful life. My past is not so good before lamictal. It partly contributed to my relationship breakdown. My moods and anxiety travelled with me for years. I have been on 225mg lamictal for about 5 years now with no noticeable side effects and I think with clarity and I seem to have much more energy. I cannot jump into a long term relationship at the moment as I am caring for my self and trying to cope with work and my well being, but there have been big strides forwards - my experience with Lamictal has been very positive - thank you - Ed"

9 / 10
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58 Report
  • Tex
  • September 6, 2019

"I am on my third month of the med using for anxiety. I was on 25mg and just went to 50mg this past week. It has helped with my anxiety. I am now able to go out places and not freak out. I rather stayed home before but I can do more now without the anxiety. I also use Lutuda for bipolar and Ambien at night. Since starting this, it has truly helped me all around. I have lost some weight and had a bad acne break out, dizziness and memory loss but I’m going to continue it to see what happens. Thanks"

10 / 10
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50 Report
  • Walker
  • Taken for 2 to 5 years
  • September 28, 2019

"I love lamictal. I have anxiety, depression and epilepsy. I can’t take SSRI’s because they are too activating for me. Lamictal helps so much with my anxiety depression and racy thoughts. Lamictal is not that activating however it keeps me up at night so I started taking it in the morning. I take it along with a lose dose of Topamax and they both help with my mood too."

10 / 10
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48 Report
  • vistard
  • April 15, 2015

"I have been on a small dose of this for about a month. It has done wonders for me! I have struggled with anxiety my entire life and have been on several different meds over the years. This has really helped to calm me down. I have even lost about 7 lbs over the past month because it is curbing my desire for food. Everyone notices the difference."

10 / 10
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  • Hero
  • Taken for 2 to 5 years
  • February 5, 2024

"I have been suffering from Bipolar 2 disorder + Anxiety (Generalized anxiety disorder) for the last 6 years. I started with antidepressants (XET 25 every day) (to cure anxiety), but it led to rapid cycling. Then I removed antidepressants and started Lamotrigine 300 OD every day. I am definitely more stable on Lamotrigine 300 OD. No more highs and lows of mood. But, some anxiety still persists (due to leaving antidepressants altogether). Curing a case of bipolar 2 + general anxiety is always tough. Because, General Anxiety is cured by antidepressants and Bipolar 2 is cured by mood stabilizers. But antidepressants cause rapid cycling. This was a problem in my case. Anyways, now coping up well with Lamotrigine 300 OD + 90 - 120 mins of daily exercise and once a week therapy. (Although, personally I think therapy isn't of much use in cases where the problem is more genetic and less due to any trauma/incident of emotional factors as such.)"

8 / 10
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  • Anna
  • Taken for less than 1 month
  • March 9, 2023

"This drug has pretty much changed my life. I've had an anxiety and panic disorder since l was a child and recently l had panic attacks most of the day. I felt hopeless as Venlafaxine wasn't helping. My panic and anxiety pretty much vanished after the 3rd dose. I feel like myself again which l didn't think it was possible."

10 / 10
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15 Report
  • JenRe...
  • July 15, 2017

"I never knew I would ever be able to feel normal again, whatever normal is? Anyway, I too have struggled with anxiety and depression/PTSD for over 20 yrs. I began taking Lamotrigine a couple of months ago and literally within a couple of days, I noticed that big ball of anxiousness I used to feel in my chest was gone.. I started with .25 mg and now I'm at 200 mg and am feeling way better.. the downside, if you want to call it that, is that I am starting to have feelings again. I cry at almost everything but it's appropriate feelings that I think I was prevented from feeling because of the psyche meds I took for so long that did nothing but ruin my life and give me terrible side effects. I am grateful to have found this medication."

10 / 10
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  • My Ni...
  • Taken for 1 to 6 months
  • September 26, 2018

"This is one of the only medications I’ve had help with anxiety. Although it doesn’t take care of the issue entirely (at 150mg currently) I have noticed some improvement. I’ve tried around 15 to 20 other medications and have had no luck other than with gabapentin and that only helped for around a month before I’d need to increase dosage again. My rating is more based of how it’s the only thing to help over how much it has helped me I will review this medication again in the future under the same nickname in around 6 months as long as I’m still taking it (and remember to do so). Hopefully this helps the general public in some way."

8 / 10
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44 Report
  • firefly
  • Taken for 1 to 6 months
  • May 3, 2022

"I NEVER leave reviews for meds, but this has literally been life changing! I've been in a dark hole for over 2 years that no SSRI/SNRI and other meds could help. Since starting Lamotrogine I've had no panic attacks and my anxiety for the first time ever has decreased significantly. I'm so relaxed and my anxiety finally isn't controlling my life. I was having panic attacks up to 3 x daily some days and was in the hospital multiple times. I was so afraid to start this med after so many failed attempts with other medications."

10 / 10
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20 Report
  • mmoreau
  • Taken for 1 to 6 months
  • September 22, 2023

"As someone diagnosed with OCD, PTSD, ASD, and ADHD, I cannot explain how bad my anxiety was or how I could NEVER relax. Well, I stopped taking benzos 3-4 months ago (over the years, I found they were making it worse) and started Lamotrigine about 8 weeks ago. I cannot explain what an incredible difference it has made. I feel like for years the swirling thoughts and feelings had me gagged, and all the world saw was a mask, and that the person behind the mask is finally able to speak. I can RELAX, watch TV at night, and drift off to sleep. I still feel ALL of my emotions and don't have any weird sensations or sexual side effects like SSRIs (it's actually BETTER now). I feel like I've lost NOTHING except the excess intrusive thoughts and spiraling emotions. My mind has slowed down, but I don't feel dumb. Actually, I feel wittier and clever again since I'm able to be myself. If nothing else has ever really worked for you, it's worth trying, even for off-label things."

10 / 10
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8 Report
  • Loz
  • Taken for 1 to 6 months
  • April 17, 2021

"I have been having really good results with lamotrigine for anxiety. Tried numerous SSRI’s, SNRI’s, Buspar, Pregabalin and nothing seemed to work, everything was too activating. I’ve been on clonazepam for around 6 years and I’ve managed to reduce my dose of this by 50% already whilst taking lamotrigine. My outlook on life has also changed for the better. If you have tried the drugs above and found them too activating or in-affective definitely try this. I’ve been using it for 8 weeks at 100mg per day. Not side effects at all."

9 / 10
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26 Report
  • Jfb
  • Taken for 1 to 6 months
  • May 28, 2019

"Lamictal made my anxiety worse. With each increase in dosage I became more agitated. I stopped at 100mg and stayed on it for one month; during that month I experienced more panic attacks than I'd ever had in such a short time. My dr weaned me off and my anxiety got better. We are now trying a different medication."

1 / 10
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36 Report
  • Sally
  • Taken for 1 to 6 months
  • March 3, 2022

"I was on Lexapro for years when I decided to step off. The process was slow and difficult, and I experienced brain zaps and other scary side effects. About a year later I had a severe mental breakdown and ended up in a crisis center. I was completely hopeless. Frightened. And experienced a primal fear. A fear you get when being chased by a wild animal. I saw a psych and she started me on Lamotrigine - and slowly went up over the course of three months to 200 mgs. I am four months into this medication and am so proud to say that I haven’t had a panic attack in a month. Not long ago I had them every single day. I experienced none of the side effects that SSRI’s gave me and I feel like I’m getting control of my life back. I’m so happy I gave medication another try. There is no shame in taking meds. You deserve to feel your best and love this one life we have to the fullest."

10 / 10
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19 Report
  • anxio...
  • Taken for 1 to 6 months
  • January 2, 2022

"I was feeling a bit overwhelmed at work as I had discontinued my antidepressants (with permission of my prescriber) for over 6 months. I really didn't want to go back to the same prescriber so I opted for an app service. They prescribed lamotrigine as a mood stabilizer. The first two days on this medication I felt worst than I had ever felt in my life. Suicidal thoughts just popped out of nowhere. It was really scary. I felt so depressed and in emotional pain and hopeless. I couldn't sleep. If I slept, I had vivid dreams and night sweats. I told the prescriber and they said side effects should wean in 5 days. So, I continued taking lamotrigine for about a month. The suicidal thoughts kinda went away and the impending doom feeling on the pit of my stomach got better. However, I had horrible headaches, vivid dreams every night and insomnia. The anxiety was constant and worse than before I started taking lamotrigine and this was only 25mg a day. I finally stopped taking it altogether."

1 / 10
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20 Report
  • Trinak
  • Taken for less than 1 month
  • February 8, 2020

"Lexapro worked for years then stopped. Tried multiple other meds without success. Dr though we’d try lam as a mood stabilizer. First 2 days I felt a weird “ disconnected” feeling but that left. I had internal tremor in the mornings which lasted till noon followed by a mild mania/ restlessness in afternoon. I was definitely cognitively sharper. By evening I would feel a bit of a crash/ low. But then it started to cause nightmares for me, waking multiple times at night in panic and sweating (I have prior trauma). So too sum things up, tremor, mania and nightmares were not doing my anxiety and depression any good. I slowly reduced and stopped this med as it wasn’t right for me."

2 / 10
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31 Report
  • Heart...
  • Taken for less than 1 month
  • October 17, 2021

"My mother just committed suicide after being on this medication for less than a week. Reading about the side effects. It says in can double your risk of suicidal thoughts. Not sure how this medication is even legal. She was overall okay mindset before starting this stuff."

1 / 10
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21 Report
  • Bella
  • Taken for 1 to 6 months
  • September 26, 2021

"I was diagnosed with anxiety/depression at 19. I saw a psych who gave me SSRI's and have been on them most of my life. Fast forward 45 years Recently had a panic attack so severe that I was on the verge of a stroke. I immediately saw a psych who told me I had been misdiagnosed all those years and that in fact I was Bipolar 2. He prescribed Lamictal 25 mg. The first 2 days I felt like I was in a fog and a little bit nauseated. Called my Dr and he recommended taking it at night. What a difference! He slowly weaned me off Celexa and Buspar and slowly increased the Lamictal. I am now stable on 100mg at night. No weight gain, and I'm back in the gym weight training. No more panic attacks. I'm a bit more emotional but I think it's situational as I just lost my dad 4 months ago. I highly recommend it!"

10 / 10
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21 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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