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Arginine Vasopressin Disorder

Medically reviewed by Drugs.com. Last updated on May 4, 2025.

What is arginine vasopressin disorder (AVD)?

AVD is a condition that causes frequent urination. The amount of urine you make is controlled by antidiuretic hormone (ADH). ADH is made in a part of the brain called the hypothalamus. ADH is stored and released by the pituitary gland. The 2 most common types of AVD are arginine vasopressin deficiency (AVP-D) and arginine vasopressin resistance (AVP-R).

What causes AVP-D?

Arginine vasopressin deficiency (AVP-D) occurs when your body does not make or release enough ADH. AVP-D can be caused by any of the following:

What causes AVP-R?

Arginine vasopressin resistance (AVP-R) occurs when your kidneys do not respond properly to ADH. AVP-R can be caused by any of the following:

What other signs and symptoms may I have with AVD?

You may have any of the following:

How is AVD diagnosed?

Your healthcare provider will ask about your medical history, symptoms, and the medicines you take. Tell your provider if you have a family history of AVD. You may need any of the following:

How is AVD treated?

Treatment depends on the type of AVD you have and the cause. You may need to stop taking certain medicines if that is the cause of your condition. Your healthcare provider will work with you to treat any condition that is causing AVD. You may need any of the following:

Treatment options

The following list of medications are related to or used in the treatment of this condition.

View more treatment options

How can I manage my symptoms?

Call your local emergency number (911 in the US) or have someone call if:

When should I seek immediate care?

When should I call my doctor?

Care Agreement

You have the right to help plan your care. Learn about your health condition and how it may be treated. Discuss treatment options with your healthcare providers to decide what care you want to receive. You always have the right to refuse treatment. The above information is an educational aid only. It is not intended as medical advice for individual conditions or treatments. Talk to your doctor, nurse or pharmacist before following any medical regimen to see if it is safe and effective for you.

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