Generic Name: clorazepate (klor-AZ-e-pate)
Brand Name: Tranxene T-Tab
Tranxene T-Tab is used for:
Treating anxiety disorders, certain types of seizures, and symptoms of alcohol withdrawal. It may also be used for other conditions as determined by your doctor.
Tranxene T-Tab is a benzodiazepine. It works by slowing down the movement of chemicals in the brain. This results in a reduction in nervous tension (anxiety) and may cause some drowsiness.
Do NOT use Tranxene T-Tab if:
- you are allergic to any ingredient in Tranxene T-Tab
- you are taking sodium oxybate (GHB)
- you have narrow-angle glaucoma or severe liver disease
Contact your doctor or health care provider right away if any of these apply to you.
Before using Tranxene T-Tab:
Some medical conditions may interact with Tranxene T-Tab. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicines, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have glaucoma, liver or kidney problems, seizures, muscle problems, a blood disorder, or lung problems
- if you have a history of mental or mood problems (eg, depression), suicidal thoughts or actions, or psychosis
- if you have a history of alcohol or substance abuse or dependence
Some MEDICINES MAY INTERACT with Tranxene T-Tab. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Hydantoins (eg, phenytoin) or rifampin because they may decrease Tranxene T-Tab's effectiveness
- Cimetidine, clozapine, disulfiram, HIV protease inhibitors (eg, ritonavir), hormonal birth control (eg, birth control pills), methadone, nefazodone, omeprazole, sodium oxybate (GHB), or valproic acid because side effects, such as confusion and increased drowsiness, may occur
This may not be a complete list of all interactions that may occur. Ask your health care provider if Tranxene T-Tab may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Tranxene T-Tab:
Use Tranxene T-Tab as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take Tranxene T-Tab by mouth with or without food.
- If you also take clozapine, do not take it within 2 hours before or after taking Tranxene T-Tab. These doses must be separated. Check with your doctor if you have questions.
- Do not suddenly stop taking Tranxene T-Tab. You may have an increased risk of serious side effects.
- If you miss a dose of Tranxene T-Tab and are using it regularly, take it as soon as possible. If you do not remember until later, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Tranxene T-Tab.
Important safety information:
- Tranxene T-Tab may cause blurred vision, dizziness, drowsiness, or lightheadedness. These effects may be worse if you take it with alcohol or certain medicines. Use Tranxene T-Tab with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Tranxene T-Tab; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- The risk of Tranxene T-Tab becoming habit-forming may be greater if you take Tranxene T-Tab in high doses or for a long time. Do NOT take more than the recommended dose or take for longer than prescribed without checking with your doctor.
- Patients who take Tranxene T-Tab may be at increased risk for suicidal thoughts or actions. The risk may be greater in patients who have had suicidal thoughts or actions in the past. Watch patients who take Tranxene T-Tab closely. Contact the doctor at once if new, worsened, or sudden symptoms such as depressed mood; anxious, restless, or irritable behavior; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
- Lab tests, including complete blood cell counts, liver and kidney tests, may be performed while you use Tranxene T-Tab. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Use Tranxene T-Tab with caution in the ELDERLY; they may be more sensitive to its effects.
- Tranxene T-Tab should be used with extreme caution in CHILDREN younger than 9 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: Tranxene T-Tab has been shown to cause harm to the fetus. If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tranxene T-Tab while you are pregnant. Tranxene T-Tab is found in breast milk. Do not breast-feed while taking Tranxene T-Tab.
When used for long periods of time or at high doses, Tranxene T-Tab may not work as well and may require higher doses to obtain the same effect as when originally taken. This is known as TOLERANCE. Talk with your doctor if Tranxene T-Tab stops working well. Do not take more than prescribed.
Some people who use Tranxene T-Tab for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction.
If you suddenly stop taking Tranxene T-Tab, you may experience WITHDRAWAL symptoms.
Possible side effects of Tranxene T-Tab:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Blurred vision; clumsiness; confusion; dizziness; drowsiness; dry mouth; headache; lightheadedness; nervousness; stomach upset; unsteadiness; unusual weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); decreased urination or change in the amount of urine produced; double vision; new or worsening mental or mood changes (eg, depression, agitation, anxiety, panic attacks, aggressiveness, impulsiveness, irritability, hostility, exaggerated feeling of well-being, restlessness, inability to sit still); new or worsening seizures; slurred speech; suicidal thoughts or actions; tremor; trouble sleeping.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include clumsiness; confusion; deep sleep; drowsiness; impaired coordination; loss of consciousness; slow reflexes.Proper storage of Tranxene T-Tab:
Store Tranxene T-Tab between 68 and 77 degrees F (20 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tranxene T-Tab out of the reach of children and away from pets.
- If you have any questions about Tranxene T-Tab, please talk with your doctor, pharmacist, or other health care provider.
- Tranxene T-Tab is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Tranxene T-Tab or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Tranxene T-Tab. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Tranxene T-Tab. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Tranxene T-Tab.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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- Drug class: benzodiazepines
Other brands: Tranxene SD