Generic Name: maraviroc (MAR-a-VIR-ok)
Brand Name: Selzentry
Liver problems have been reported in some patients taking Selzentry. An allergic reaction may occur before liver problems develop. Contact your doctor right away if you develop a rash; hives; itching; trouble breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; yellowing of the eyes or skin; dark urine; pale stools; loss of appetite; or severe stomach pain.
Selzentry is used for:
Treating patients with a certain type of HIV infection (CCR5-tropic HIV-1). It is used along with other HIV medicines.
Selzentry is a CCR5 coreceptor antagonist. It works by blocking the virus from entering cells.
Do NOT use Selzentry if:
- you are allergic to any ingredient in Selzentry
- you are taking St. John's wort
- you have severe kidney problems or you are on dialysis and you take certain other medicines. Talk to your doctor before taking Selzentry if you have kidney problems
Contact your doctor or health care provider right away if any of these apply to you.
Before using Selzentry:
Some medical conditions may interact with Selzentry. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of liver problems (eg, hepatitis B or C), or kidney problems
- if you have a history of heart problems, or if you are at risk of heart problems
- if you are on dialysis
- if you have a history of low blood pressure or dizziness when you stand up
- if you are taking medicine to lower your blood pressure
Some MEDICINES MAY INTERACT with Selzentry. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Azole antifungals (eg, itraconazole, ketoconazole), delavirdine, macrolide antibiotics (eg, clarithromycin), nefazodone, protease inhibitors (eg, amprenavir, boceprevir, ritonavir), or telithromycin because they may increase the risk of Selzentry's side effects
- Barbiturates (eg, phenobarbital), carbamazepine, efavirenz, etravirine, hydantoins (eg, phenytoin), rifamycins (eg, rifampin), or St. John's wort because they may decrease Selzentry's effectiveness
This may not be a complete list of all interactions that may occur. Ask your health care provider if Selzentry may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use Selzentry:
Use Selzentry as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Selzentry comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Selzentry refilled.
- Take Selzentry by mouth with or without food.
- Swallow Selzentry whole. Do not break, crush, or chew before swallowing.
- Taking Selzentry at the same time(s) each day will help you remember to take it.
- Take Selzentry on a regular schedule to get the most benefit from it.
- Continue to take Selzentry even if you feel well. Do not miss any doses.
- If you miss a dose of Selzentry, take it as soon as possible. If your next dose is less than 6 hours away, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use Selzentry.
Important safety information:
- Selzentry may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Selzentry with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Selzentry may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. Your risk may be greater if you have severe kidney problems. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Do NOT take more than the recommended dose or use more often than prescribed without checking with your doctor.
- Certain other medicines for HIV (eg, HIV protease inhibitors, delavirdine, efavirenz) may increase the side effects of Selzentry or decrease its effectiveness. Talk with your doctor about all of your HIV medicines. Do not start, stop, or change the dose of any HIV medicine unless your doctor tells you to.
- Serious and sometimes fatal skin reactions and allergic reactions have been reported in some patients taking Selzentry. Contact your doctor right away if you develop blisters or sores in the mouth; fever; general ill feeling; muscle or joint aches; rash, including red, swollen, blistered, or peeling skin; red or swollen eyes; severe tiredness; trouble breathing; swelling of the mouth or face; symptoms of kidney problems (eg, decreased urination); or symptoms of liver problems (eg, dark urine, loss of appetite, pale stools, severe or persistent nausea or vomiting, stomach pain, yellowing of the eyes or skin).
- Selzentry may improve immune system function. This may reveal hidden infections in some patients. Tell your doctor right away if you notice symptoms of infection (eg, fever, sore throat, weakness, cough, shortness of breath) after you start Selzentry.
- Selzentry may increase the risk of developing an infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills. Discuss any questions or concerns with your doctor.
- It is possible that Selzentry may increase the risk of developing cancer. No increase in cancer cases has been seen in patients who take Selzentry. Discuss any questions or concerns with your doctor.
- Selzentry is not a cure for HIV infection. Patients may still get illnesses and infections associated with HIV. Remain under the care of your doctor.
- When your medicine supply is low, get more from your doctor or pharmacist as soon as you can. Do not stop taking Selzentry, even for a short period of time. If you do, the virus may grow resistant to the medicine and become harder to treat.
- Selzentry does not stop the spread of HIV to others through blood or sexual contact. Do not have any kind of sex without protection (eg, latex or polyurethane condoms) if you have HIV infection. Do not share needles, injection supplies, or items like toothbrushes or razors. Talk with your health care provider about ways to prevent the spread of HIV to others.
- Lab tests, including liver function, may be performed while you use Selzentry. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Selzentry should not be used in CHILDREN younger than 16 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Selzentry while you are pregnant. It is not known if this medicine is found in breast milk. Women infected with HIV should not breast-feed. There is a risk of passing the HIV infection or Selzentry to the baby.
Possible side effects of Selzentry:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Constipation; cough; diarrhea; dizziness; muscle or joint pain; runny or stuffy nose; sinus inflammation; stomach pain; trouble sleeping.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody diarrhea; burning, numbness, or tingling; chest, jaw, or arm pain; confusion; depression; difficult or painful urination; fainting; fever, chills, or sore throat; flu-like symptoms; one-sided weakness; red, swollen, blistered, or peeling skin; seizures; severe muscle pain; severe or persistent dizziness; severe or persistent stomach pain; shortness of breath; slurred speech; sores or white patches in the mouth; sudden, severe nausea or vomiting; sudden, unusual sweating or weakness; swelling of the hands, ankles, legs, or feet; symptoms of liver problems (eg, yellowing of the eyes or skin, dark urine, pale stools, loss of appetite, nausea, unusual tiredness, vomiting); unusual lumps, skin growths, or skin changes; unusual tiredness or weakness; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fainting; severe or persistent dizziness.Proper storage of Selzentry:
Store Selzentry between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Selzentry out of the reach of children and away from pets.
- If you have any questions about Selzentry, please talk with your doctor, pharmacist, or other health care provider.
- Selzentry is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take Selzentry or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Selzentry. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Selzentry. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using Selzentry.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
More about Selzentry (maraviroc)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Images
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 2 Reviews – Add your own review/rating
- Drug class: chemokine receptor antagonist