Generic Name: risperidone (ris-PER-i-done)
Brand Name: Risperdal
Risperidone solution is an atypical antipsychotic. It may increase the risk of death when used to treat mental problems caused by dementia in elderly patients. Most of the deaths were linked to heart problems or infection. Risperidone solution is not approved to treat mental problems caused by dementia.
Risperidone solution is used for:
Treating schizophrenia or bipolar disorder. It is used to treat irritability caused by autistic disorder. It may also be used for other conditions as determined by your doctor.
Risperidone solution is an atypical antipsychotic. It works by affecting certain substances in the brain.
Do NOT use risperidone solution if:
- you are allergic to any ingredient in risperidone solution
- you are taking metoclopramide
Contact your doctor or health care provider right away if any of these apply to you.
Before using risperidone solution:
Some medical conditions may interact with risperidone solution. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of seizures, heart problems (eg, heart failure, slow or irregular heartbeat), abnormal electrocardiogram (ECG), heart attack, stroke, blood vessel problems, high or low blood pressure, high cholesterol or triglyceride levels, or low white blood cell levels
- if you have a history of kidney or liver problems, stomach or bowel problems (eg, narrowing, blockage), neuroleptic malignant syndrome (NMS), suicidal thoughts or attempts, or alcohol abuse or dependence
- if you have diabetes or are very overweight, or if a family member has had diabetes
- if you have Alzheimer disease, dementia, Parkinson disease, or esophagus problems (eg, trouble swallowing)
- if you have had high blood prolactin levels or a history of certain types of cancer (eg, breast, pancreas, pituitary, brain), or if you are at risk for breast cancer
- if you are dehydrated, have low blood volume, drink alcohol, or will be exposed to very high or very low temperatures
Some MEDICINES MAY INTERACT with risperidone solution. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Alpha-blockers (eg, doxazosin) or medicine for high blood pressure because the risk of low blood pressure and fainting may be increased
- Anticholinergics (eg, scopolamine) because the risk of overheating may be increased
- Tramadol because the risk of seizures may be increased
- Abiraterone, clozapine, metoclopramide, or selective serotonin reuptake inhibitors (SSRIs) (eg, fluoxetine, paroxetine) because they may increase the risk of risperidone solution's side effects
- Carbamazepine, phenobarbital, phenytoin, or rifampin because they may decrease risperidone solution's effectiveness
- Dopamine receptor agonists (eg, pramipexole) or levodopa because their effectiveness may be decreased by risperidone solution
This may not be a complete list of all interactions that may occur. Ask your health care provider if risperidone solution may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use risperidone solution:
Use risperidone solution as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- Take risperidone solution by mouth with or without food.
- Risperidone solution may be taken by mouth directly from the dropper or mixed with water, coffee, orange juice, or low-fat milk. Do NOT mix risperidone solution with cola or tea.
- Use the dropper that comes with risperidone solution to measure your dose. Ask your pharmacist for help if you are unsure how to measure your dose.
- Take risperidone solution on a regular schedule to get the most benefit from it. Taking risperidone solution at the same time each day will help you remember to take it.
- Continue to take risperidone solution even if you feel well. Do not miss any doses.
- If you miss a dose of risperidone solution, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.
Ask your health care provider any questions you may have about how to use risperidone solution.
Important safety information:
- Risperidone solution may cause drowsiness, dizziness, light-headedness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use risperidone solution with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Do not drink alcohol while you are using risperidone solution.
- Check with your doctor before taking medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using risperidone solution; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
- Risperidone solution may cause dizziness, light-headedness, or fainting; alcohol, hot weather, exercise, or fever may increase these effects. To prevent them, sit up or stand slowly, especially in the morning. Sit or lie down at the first sign of any of these effects.
- Do not become overheated in hot weather or while you are being active; heatstroke may occur.
- Patients who have bipolar (manic-depressive) illness, or if their family members have had it, may be at increased risk for suicidal thoughts or actions. Watch patients who take risperidone solution closely. Contact the doctor at once if new, worsened, or sudden symptoms such as anxious, restless, or irritable behavior; depressed mood; panic attacks; or any unusual change in mood or behavior occur. Contact the doctor right away if any signs of suicidal thoughts or actions occur.
- Risperidone solution may raise your blood sugar. High blood sugar may make you feel confused, drowsy, or thirsty. It can also make you flush, breathe faster, or have a fruit-like breath odor. If these symptoms occur, tell your doctor right away.
- Diabetes patients - Check blood sugar levels closely. Ask your doctor before you change the dose of your diabetes medicine.
- Risperidone solution may lower the ability of your body to fight infection. Avoid contact with people who have colds or infections. Tell your doctor if you notice signs of infection like fever, sore throat, rash, or chills.
- NMS is a possibly fatal syndrome that can be caused by risperidone solution. Symptoms may include fever; stiff muscles; confusion; abnormal thinking; fast or irregular heartbeat; or sweating. Contact your doctor at once if you have any of these symptoms.
- Some patients who take risperidone solution may develop muscle movements that they cannot control. This is more likely to happen in elderly patients, especially women. The chance that this will happen or that it will become permanent is greater in those who take risperidone solution in higher doses or for a long time. Muscle problems may also occur after short-term treatment with low doses. Tell your doctor at once if you have muscle problems with your arms; legs; or your tongue, face, mouth, or jaw (eg, tongue sticking out, puffing of cheeks, mouth puckering, chewing movements) while taking risperidone solution.
- Risperidone solution may increase the amount of a certain hormone (prolactin) in your blood. Symptoms may include enlarged breasts, missed menstrual period, decreased sexual ability, or nipple discharge. Contact your doctor right away if you experience any of these symptoms.
- Risperidone solution may rarely cause a prolonged, painful erection. This could happen even when you are not having sex. If this is not treated right away, it could lead to permanent sexual problems such as impotence. Contact your doctor right away if this happens.
- Lab tests, including fasting blood glucose and complete blood cell counts, may be performed while you use risperidone solution. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
- Risperidone solution may cause weight gain. Your weight may need to be monitored while you take risperidone solution.
- Use risperidone solution with caution in the ELDERLY; they may be more sensitive to its effects, especially dizziness when standing or uncontrolled muscle movements.
- Risperidone solution should be used with extreme caution in CHILDREN younger than 5 years old; safety and effectiveness in these children have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking risperidone solution while you are pregnant. Using risperidone solution during the third trimester may result in uncontrolled muscle movements or withdrawal symptoms in the newborn. Discuss any questions or concerns with your doctor. Risperidone solution is found in breast milk. Do not breast-feed while taking risperidone solution.
Possible side effects of risperidone solution:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Anxiety; back pain; blurred vision; constipation; cough; diarrhea; dizziness; drowsiness; dry mouth; fatigue; headache; increased appetite; increased saliva production; indigestion; light-headedness; mild sore throat; nausea; restlessness; runny or stuffy nose; stomach pain or upset; trouble sleeping; vomiting; weight gain.
Severe allergic reactions (rash; hives; itching; difficulty breathing or swallowing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); abnormal thoughts; confusion; drooling; fainting; fast, slow, or irregular heartbeat; fever, chills, or persistent sore throat; inability to control urination; increased sweating; new or worsening mental or mood changes (eg, aggression, agitation, depression, severe anxiety); one-sided weakness; seizures; severe dizziness; stiff or rigid muscles; suicidal thoughts or attempts; symptoms of high blood sugar (eg, increased thirst, hunger, or urination; unusual weakness); tremor; trouble concentrating, speaking, or swallowing; trouble sitting still; trouble walking or standing; uncontrolled muscle movements (eg, arm or leg movements, twitching of the face or tongue, jerking or twisting); unusual bruising; vision changes.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include fast or irregular heartbeat; severe drowsiness or dizziness; unusual muscle movements.Proper storage of risperidone solution:
Store risperidone solution between 59 and 77 degrees F (15 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep risperidone solution out of the reach of children and away from pets.
- If you have any questions about risperidone solution, please talk with your doctor, pharmacist, or other health care provider.
- Risperidone solution is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take risperidone solution or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about risperidone solution. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to risperidone solution. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using risperidone solution.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
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