Generic Name: abciximab (ab-SIX-i-mab)
Brand Name: ReoPro
ReoPro is used for:
Preventing serious heart problems in patients undergoing a procedure called percutaneous coronary intervention (PCI). It is also used in certain patients with unstable angina (chest pain) to prevent serious heart problems when PCI is planned. ReoPro is used in combination with other medicines.
ReoPro is a platelet aggregation inhibitor. It works by blocking platelets from sticking together to form blood clots.
Do NOT use ReoPro if:
- you are allergic to any ingredient in ReoPro or to murine proteins
- you have active internal bleeding, low blood platelet count, or other bleeding or clotting problems
- you have had stomach, bowel, or urinary bleeding or major surgery or trauma within the past 6 weeks
- you have had a stroke within the past 2 years
- you have severe uncontrolled high blood pressure or a history of blood vessel inflammation (vasculitis)
- you have had a growth or cancer of the brain, an aneurysm, or problems with blood vessels in the brain
- you are or will be receiving dextran by injection
- you are receiving or have received an anticoagulant (eg, warfarin) within the last 7 days
Contact your doctor or health care provider right away if any of these apply to you.
Before using ReoPro:
Some medical conditions may interact with ReoPro. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
- if you are pregnant, planning to become pregnant, or are breast-feeding
- if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
- if you have allergies to medicines, foods, or other substances
- if you have a history of bleeding or clotting problems
Some MEDICINES MAY INTERACT with ReoPro. Tell your health care provider if you are taking any other medicines, especially any of the following:
- Anticoagulants (eg, warfarin, heparin), dipyridamole, nonsteroidal anti-inflammatory drugs (NSAIDs) (eg, ibuprofen), ticlopidine, or thrombolytics (tissue plasminogen activators) because the risk of bleeding may be increased
This may not be a complete list of all interactions that may occur. Ask your health care provider if ReoPro may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
How to use ReoPro:
Use ReoPro as directed by your doctor. Check the label on the medicine for exact dosing instructions.
- ReoPro is usually administered as an injection at your doctor's office, hospital, or clinic. Ask your doctor any questions that you may have about ReoPro.
- If you miss a dose of ReoPro, contact your doctor right away.
Ask your health care provider any questions you may have about how to use ReoPro.
Important safety information:
- ReoPro may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use ReoPro with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
- Severe and sometimes fatal bleeding has occurred in patients taking ReoPro. The risk may be greater when used with medicines that thin the blood. Avoid activities that may cause bruising or injury. Contact your doctor right away if you experience unusual bruising or bleeding (eg, bleeding gums; nosebleeds; bleeding in the eye; blood in the urine; black, bloody, or tarry stools; coughing up blood; vomiting blood or material that looks like coffee grounds; severe or unusual vaginal bleeding); severe stomach pain; confusion; or severe or persistent headache or dizziness.
- LAB TESTS, including complete blood cell counts and blood clotting tests, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
- ReoPro is not recommended for use in CHILDREN; safety and effectiveness have not been confirmed.
- PREGNANCY and BREAST-FEEDING: If you become pregnant, discuss with your doctor the benefits and risks of using ReoPro during pregnancy. It is not known if this medicine is found in breast milk. Do not breast-feed while taking ReoPro.
Possible side effects of ReoPro:
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur:
Back pain; dizziness; headache; nausea; pain at injection site; stomach pain; vomiting.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); chest pain; chills; fainting; fever; increased menstrual bleeding; pain, redness, or swelling at the injection site; severe or persistent dizziness, headache, or light-headedness; slow heartbeat; swelling of the hands, ankles, or feet.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
If OVERDOSE is suspected:
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.Proper storage of ReoPro:
ReoPro is handled and stored by a health care provider. Keep ReoPro out of the reach of children and away from pets.
- If you have any questions about ReoPro, please talk with your doctor, pharmacist, or other health care provider.
- ReoPro is to be used only by the patient for whom it is prescribed. Do not share it with other people.
- If your symptoms do not improve or if they become worse, check with your doctor.
- Check with your pharmacist about how to dispose of unused medicine.
This information should not be used to decide whether or not to take ReoPro or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about ReoPro. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to ReoPro. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your health care provider for complete information about the risks and benefits of using ReoPro.
Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.