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Pseudoephedrine/ dexchlorpheniramine/ chlophedianol liquid

Generic Name: pseudoephedrine/dexchlorpheniramine/chlophedianol (SOO-doe-e-FED-rin/DEX-klor-fen-IR-a-meen/KLOE-fe-DYE-a-nol)
Brand Name: Examples include Panatuss PED and Vanacof

Pseudoephedrine/ dexchlorpheniramine/ chlophedianol liquid is used for:

Relieving symptoms of sinus congestion, runny nose, sneezing, itchy nose or throat, itchy or watery eyes, and cough due to colds, hay fever, and other upper respiratory allergies. It may also be used for other conditions as determined by your doctor.

Pseudoephedrine/dexchlorpheniramine/chlophedianol liquid is a decongestant, antihistamine, and cough suppressant combination. The decongestant works by constricting blood vessels and reducing swelling in the nasal passages. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The cough suppressant works in the brain to help decrease the cough reflex to reduce a dry cough.

Do NOT use pseudoephedrine/ dexchlorpheniramine/ chlophedianol liquid if:

  • you are allergic to any ingredient in pseudoephedrine/dexchlorpheniramine/chlophedianol liquid
  • you have severe or uncontrolled high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems
  • you are unable to urinate or are having an asthma attack
  • you are taking droxidopa or sodium oxybate (GHB), or you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using pseudoephedrine/ dexchlorpheniramine/ chlophedianol liquid:

Some medical conditions may interact with pseudoephedrine/dexchlorpheniramine/chlophedianol liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have a history of adrenal gland problems (eg, adrenal gland tumor), heart problems (eg, fast, slow, or irregular heartbeat; heart disease), high or low blood pressure, low blood volume, diabetes, blood vessel problems, stroke, glaucoma or increased pressure in the eye, seizures, mental or mood problems (eg, depression), thyroid problems, or trouble sleeping
  • if you have a history of asthma, chronic obstructive pulmonary disease (COPD), or other lung or breathing problems (eg, chronic bronchitis, emphysema, sleep apnea); chronic cough; or if your cough occurs with large amounts of mucus
  • if you have a history of stomach or bowel ulcers; a blockage of your stomach, bladder, or bowels ; an enlarged prostate or other prostate problems; kidney problems; or trouble urinating
  • if you take medicine for high blood pressure or depression

Some MEDICINES MAY INTERACT with pseudoephedrine/dexchlorpheniramine/chlophedianol liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased
  • Beta-blockers (eg, propranolol), furazolidone, linezolid, MAOIs (eg, phenelzine), selective serotonin reuptake inhibitors (SSRIs) (eg, citalopram, fluoxetine), sodium oxybate (GHB), or urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk of pseudoephedrine/dexchlorpheniramine/chlophedianol liquid's side effects
  • Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by pseudoephedrine/dexchlorpheniramine/chlophedianol liquid
  • Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by pseudoephedrine/dexchlorpheniramine/chlophedianol liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if pseudoephedrine/dexchlorpheniramine/chlophedianol liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use pseudoephedrine/ dexchlorpheniramine/ chlophedianol liquid:

Use pseudoephedrine/dexchlorpheniramine/chlophedianol liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

  • Take pseudoephedrine/dexchlorpheniramine/chlophedianol liquid by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
  • Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.
  • Take pseudoephedrine/dexchlorpheniramine/chlophedianol liquid with a full glass of water (8 oz/240 mL).
  • If you miss a dose of pseudoephedrine/dexchlorpheniramine/chlophedianol liquid and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use pseudoephedrine/dexchlorpheniramine/chlophedianol liquid.

Important safety information:

  • Pseudoephedrine/dexchlorpheniramine/chlophedianol liquid may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use pseudoephedrine/dexchlorpheniramine/chlophedianol liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol while you are using pseudoephedrine/dexchlorpheniramine/chlophedianol liquid.
  • Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using pseudoephedrine/dexchlorpheniramine/chlophedianol liquid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.
  • Do not take diet or appetite control medicines while you take pseudoephedrine/dexchlorpheniramine/chlophedianol liquid without checking with your doctor.
  • Pseudoephedrine/dexchlorpheniramine/chlophedianol liquid has a decongestant, antihistamine, and cough suppressant in it. Before you start any new medicine, check the label to see if it has a decongestant, antihistamine, or cough suppressant in it too. If it does or if you are not sure, check with your doctor or pharmacist.
  • Do not use pseudoephedrine/dexchlorpheniramine/chlophedianol liquid for a cough with a lot of mucus. Do not use it for a long-term cough (eg, caused by asthma, emphysema, smoking). However, you may use it for these conditions if your doctor tells you to.
  • Do NOT take more than the recommended dose or use for longer than recommended without checking with your doctor.
  • If new symptoms occur, or if cough or nasal congestion persists for more than 1 week, goes away and returns, or occurs along with a fever, rash, or persistent headache, check with your doctor. A persistent cough may be a sign of a serious condition.
  • Pseudoephedrine/dexchlorpheniramine/chlophedianol liquid may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to pseudoephedrine/dexchlorpheniramine/chlophedianol liquid. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.
  • Pseudoephedrine/dexchlorpheniramine/chlophedianol liquid may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking pseudoephedrine/dexchlorpheniramine/chlophedianol liquid for a few days before the tests.
  • Tell your doctor or dentist that you take pseudoephedrine/dexchlorpheniramine/chlophedianol liquid before you receive any medical or dental care, emergency care, or surgery.
  • Use pseudoephedrine/dexchlorpheniramine/chlophedianol liquid with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, drowsiness, dizziness, dry mouth, nervousness, sleeplessness, and trouble urinating.
  • Caution is advised when using pseudoephedrine/dexchlorpheniramine/chlophedianol liquid in CHILDREN; they may be more sensitive to its effects, especially excitability.
  • Pseudoephedrine/dexchlorpheniramine/chlophedianol liquid should not be used in CHILDREN younger than 6 years old without first checking with the child's doctor; safety and effectiveness in these children have not been confirmed.
  • PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using pseudoephedrine/dexchlorpheniramine/chlophedianol liquid while you are pregnant. Some ingredients of pseudoephedrine/dexchlorpheniramine/chlophedianol liquid are found in breast milk. Do not breast-feed while taking pseudoephedrine/dexchlorpheniramine/chlophedianol liquid.

Possible side effects of pseudoephedrine/ dexchlorpheniramine/ chlophedianol liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Anxiety; constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; increased sweating; loss of appetite; nausea; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; fever, chills, or persistent sore throat; flushing or redness of the face; hallucinations; loss of coordination; mental or mood changes (eg depression, nervousness); numbness or tingling; seizures; severe dryness of mouth, nose, or throat; severe or persistent dizziness, drowsiness, light-headedness, or headache; severe or persistent trouble sleeping; shortness of breath; tremor; unusual bruising or bleeding; unusual tiredness or weakness; vision problems (eg, double vision, severe or persistent blurred vision).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; flushing; hallucinations; mental or mood changes; muscle spasms; seizures; severe dizziness, light-headedness, or headache; severe drowsiness; trouble breathing; unusual eye movements; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of pseudoephedrine/dexchlorpheniramine/chlophedianol liquid:

Store pseudoephedrine/dexchlorpheniramine/chlophedianol liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep pseudoephedrine/dexchlorpheniramine/chlophedianol liquid out of the reach of children and away from pets.

General information:

  • If you have any questions about pseudoephedrine/dexchlorpheniramine/chlophedianol liquid, please talk with your doctor, pharmacist, or other health care provider.
  • Pseudoephedrine/dexchlorpheniramine/chlophedianol liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.
  • If your symptoms do not improve or if they become worse, check with your doctor.
  • Check with your pharmacist about how to dispose of unused medicine.

This information should not be used to decide whether or not to take pseudoephedrine/dexchlorpheniramine/chlophedianol liquid or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about pseudoephedrine/dexchlorpheniramine/chlophedianol liquid. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to pseudoephedrine/dexchlorpheniramine/chlophedianol liquid. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using pseudoephedrine/dexchlorpheniramine/chlophedianol liquid.

Review Date: November 3, 2016

Disclaimer: This information should not be used to decide whether or not to take this medicine or any other medicine. Only your health care provider has the knowledge and training to decide which medicines are right for you. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from your health care provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.

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