- Very bad and sometimes life-threatening allergic reactions have happened with Lumizyme (alglucosidase alfa). These reactions have happened during infusion and up to 3 hours after it is done.
- Very bad reactions like kidney problems and skin reactions have happened after treatment with Lumizyme (alglucosidase alfa). These reactions have happened several weeks to 3 years after treatment started. Talk with the doctor.
- During or after the infusion, tell your doctor if you have back pain; bluish skin or nails; a burning, numbness, or tingling feeling that is not normal; chest pain; dizziness or passing out; fast or trouble breathing; fast or slow heartbeat; feeling hot or cold; feeling nervous or restless; fever or chills; flushing; headache; hives; itching; pale skin; rash; seizures; sweating more than normal; swelling; tightness in the chest or throat; upset stomach; or wheezing.
- You will be watched closely by your doctor.
- Tell your doctor if you have any heart or lung problems. If you have a reaction to Lumizyme (alglucosidase alfa), your heart or lung problem may get worse. Talk with your doctor.
Uses of Lumizyme:
- It is used to treat Pompe disease.
What do I need to tell my doctor BEFORE I take Lumizyme?
- If you have an allergy to alglucosidase alfa or any other part of Lumizyme (alglucosidase alfa).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are breast-feeding. Do not breast-feed for 24 hours after getting Lumizyme (alglucosidase alfa).
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Lumizyme (alglucosidase alfa) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Lumizyme?
- Tell all of your health care providers that you take Lumizyme (alglucosidase alfa). This includes your doctors, nurses, pharmacists, and dentists.
- If you will be getting anesthesia, talk with your doctor. The chance of a heartbeat that is not normal and sudden death caused by heart problems may be raised in some people.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Have your urine checked as you have been told by your doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Lumizyme (alglucosidase alfa) while you are pregnant.
How is this medicine (Lumizyme) best taken?
Use Lumizyme (alglucosidase alfa) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as an infusion into a vein over a period of time.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- Signs of high blood pressure like very bad headache or dizziness, passing out, or change in eyesight.
- Shortness of breath, a big weight gain, or swelling in the arms or legs.
- Feeling agitated.
- Muscle pain.
- A heartbeat that does not feel normal.
- Feeling very tired or weak.
What are some other side effects of Lumizyme?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Irritation where the shot is given.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Lumizyme?
- If you need to store Lumizyme (alglucosidase alfa) at home, talk with your doctor, nurse, or pharmacist about how to store it.
Consumer Information Use and Disclaimer
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Lumizyme (alglucosidase alfa), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Disclaimer: This information should not be used to decide whether or not to take Lumizyme (alglucosidase alfa) or any other medicine. Only the healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about Lumizyme (alglucosidase alfa). It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to Lumizyme (alglucosidase alfa). This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with the healthcare provider for complete information about the risks and benefits of using Lumizyme (alglucosidase alfa).
Review Date: February 7, 2018
More about Lumizyme (alglucosidase alfa)
- Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
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- Drug class: lysosomal enzymes
Other brands: Myozyme