Generic Name: Indinavir (in DIN a veer)
Brand Name: Crixivan
Medically reviewed on May 2, 2018
Uses of Indinavir:
- It is used to treat HIV infection.
What do I need to tell my doctor BEFORE I take Indinavir?
- If you have an allergy to indinavir or any other part of indinavir.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you take any drugs (prescription or OTC, natural products, vitamins) that must not be taken with indinavir, like certain drugs that are used for high cholesterol, migraines, or mood problems. There are many drugs that must not be taken with indinavir.
- If you are taking St. John's wort. Do not take St. John's wort with indinavir. This medicine may not work as well.
- If you are breast-feeding. Do not breast-feed while you take indinavir.
This is not a list of all drugs or health problems that interact with indinavir.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take indinavir with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Indinavir?
- Tell all of your health care providers that you take indinavir. This includes your doctors, nurses, pharmacists, and dentists.
- This medicine interacts with many other drugs. The chance of indinavir's side effects may be raised or how well indinavir works may be lowered. The chance of the other drugs' side effects may also be raised. This may include very bad, life-threatening, or deadly side effects. Check with your doctor and pharmacist to make sure that it is safe for you to take indinavir with all of your other drugs (prescription or OTC, natural products, vitamins).
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how indinavir affects you.
- If you have high blood sugar (diabetes), talk with your doctor. This medicine may raise blood sugar.
- Some people with hemophilia have had times of more bleeding when taking drugs like this one. If you have hemophilia, talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- This medicine may raise the chance of kidney stones. Be sure to drink lots of fluids while taking indinavir. Children are more likely to get kidney stones than adults.
- Very bad and sometimes deadly liver problems have happened with indinavir. Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow skin or eyes.
- A very bad and sometimes deadly type of anemia called hemolytic anemia has happened with indinavir. Call your doctor right away if you have pale skin, dizziness, fever or chills, very bad back or belly pain, dark urine, yellow skin or eyes, or you feel very tired or weak.
- This medicine is not a cure for HIV. Stay under the care of your doctor.
- This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- Birth control pills and other hormone-based birth control may not work as well to prevent pregnancy. Use some other kind of birth control also like a condom when taking indinavir.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using indinavir while you are pregnant.
How is this medicine (Indinavir) best taken?
Use indinavir as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Take with water, juice, skim milk, coffee, tea, or a light snack. Take 1 hour before or 2 hours after meals.
- If taking indinavir with ritonavir, take with food.
- Drink lots of noncaffeine liquids unless told to drink less liquid by your doctor.
- Do not take didanosine within 1 hour of indinavir.
- Keep taking indinavir as you have been told by your doctor or other health care provider, even if you feel well.
- It is important that you do not miss or skip a dose of indinavir during treatment.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it has been 2 hours or more since the missed dose, skip the missed dose and go back to the normal time.
- Do not take 2 doses at the same time or extra doses.
- If you are not sure what to do if you miss a dose, call your doctor.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of high blood sugar like confusion, feeling sleepy, more thirst, more hungry, passing urine more often, flushing, fast breathing, or breath that smells like fruit.
- Pain in side.
- Cloudy or pink-red urine.
- Bladder pain or pain when passing urine or change in how much urine is passed.
- Back pain, belly pain, or blood in the urine. May be signs of a kidney stone.
- Feeling more or less hungry.
- Chest pain or pressure.
- Weakness on 1 side of the body, trouble speaking or thinking, change in balance, drooping on one side of the face, or blurred eyesight.
- Low mood (depression).
- Very bad dizziness or passing out.
- Joint pain.
- Numbness or tingling in the mouth.
- Shortness of breath.
- Sweating a lot.
- Swelling of belly.
- Change in body fat.
- A very bad skin reaction (Stevens-Johnson syndrome/toxic epidermal necrolysis) may happen. It can cause very bad health problems that may not go away, and sometimes death. Get medical help right away if you have signs like red, swollen, blistered, or peeling skin (with or without fever); red or irritated eyes; or sores in your mouth, throat, nose, or eyes.
- Changes in your immune system can happen when you start taking drugs to treat HIV. If you have an infection that you did not know you had, it may show up when you take indinavir. Tell your doctor right away if you have any new signs after you start indinavir, even after taking it for several months. This includes signs of infection like fever, sore throat, weakness, cough, or shortness of breath.
What are some other side effects of Indinavir?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Belly pain.
- Feeling tired or weak.
- Upset stomach or throwing up.
- Back pain.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Indinavir?
- Store at room temperature.
- Store in the original container. Do not take out the antimoisture cube or packet.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about indinavir, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about indinavir
- Indinavir Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Español
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- Drug class: protease inhibitors
Other brands: Crixivan