Generic Name: Enfuvirtide (en FYOO vir tide)
Brand Name: Fuzeon
Medically reviewed on May 2, 2018
Uses of Enfuvirtide:
- It is used to treat HIV infection.
What do I need to tell my doctor BEFORE I take Enfuvirtide?
- If you have an allergy to enfuvirtide or any other part of enfuvirtide.
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
- If you are breast-feeding. Do not breast-feed while you take enfuvirtide.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take enfuvirtide with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Enfuvirtide?
For all patients taking enfuvirtide:
- Tell all of your health care providers that you take enfuvirtide. This includes your doctors, nurses, pharmacists, and dentists.
- Avoid driving and doing other tasks or actions that call for you to be alert until you see how enfuvirtide affects you.
- Do not run out of enfuvirtide.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- If you smoke, talk with your doctor.
- This medicine does not stop the spread of diseases like HIV or hepatitis that are passed through blood or having sex. Do not have any kind of sex without using a latex or polyurethane condom. Do not share needles or other things like toothbrushes or razors. Talk with your doctor.
- This medicine is not a cure for HIV. Stay under the care of your doctor.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using enfuvirtide while you are pregnant.
- If giving to your child, the dose of enfuvirtide may need to be changed as your child's weight changes. Have your child's weight checked often. Talk with the doctor before changing your child's dose.
How is this medicine (Enfuvirtide) best taken?
Use enfuvirtide as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- Keep taking enfuvirtide as you have been told by your doctor or other health care provider, even if you feel well.
- It is important that you do not miss or skip a dose of enfuvirtide during treatment.
- It is given as a shot into the fatty part of the skin on the top of the thigh, belly area, or upper arm.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- This medicine needs to be mixed before use. Follow how to mix as you were told by the doctor.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- If solution is foamy or jelly-like, wait before using.
- Move the site where you give the shot with each shot.
- Do not give into red or irritated skin.
- Do not give into a mole, scar, or bruise.
- Wash your hands before and after use.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- Take a missed dose as soon as you think about it.
- If it is close to the time for your next dose, skip the missed dose and go back to your normal time.
- Do not take 2 doses at the same time or extra doses.
See also: Dosage Information (in more detail)
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of a pancreas problem (pancreatitis) like very bad stomach pain, very bad back pain, or very bad upset stomach or throwing up.
- Signs of skin infection like oozing, heat, swelling, redness, or pain.
- Very bad irritation where the shot was given.
- Fever or chills.
- Very upset stomach or throwing up.
- Very bad dizziness or passing out.
- Swelling in the arms or legs.
- Swollen gland.
- Low mood (depression).
- Changes in your immune system can happen when you start taking drugs to treat HIV. If you have an infection that you did not know you had, it may show up when you take enfuvirtide. Tell your doctor right away if you have any new signs after you start enfuvirtide, even after taking it for several months. This includes signs of infection like fever, sore throat, weakness, cough, or shortness of breath.
- Very bad and sometimes deadly kidney problems have happened with enfuvirtide. Call your doctor right away if you are unable to pass urine or if you have blood in the urine or a change in the amount of urine passed.
- A nervous system problem called Guillain-Barre syndrome has happened with enfuvirtide. Sometimes, this has been deadly. Call your doctor right away if you have weakness or a burning, numbness, or tingling feeling that is not normal.
- Some people taking enfuvirtide may get pneumonia more often than people not taking enfuvirtide. It is not clear if this effect is caused by enfuvirtide. Call your doctor right away if you have a cough, fever, shortness of breath, or trouble breathing.
What are some other side effects of Enfuvirtide?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Not able to sleep.
- Irritation where the shot is given.
- Loose stools (diarrhea).
- Upset stomach.
- Feeling tired or weak.
- Not hungry.
- Weight loss.
- Muscle pain.
- Sinus irritation.
- Hard stools (constipation).
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
See also: Side effects (in more detail)
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Enfuvirtide?
- Store at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Use right away after mixing or you may store in a refrigerator for up to 24 hours.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about enfuvirtide, please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about enfuvirtide
- Enfuvirtide Side Effects
- During Pregnancy or Breastfeeding
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 4 Reviews – Add your own review/rating
- Drug class: miscellaneous antivirals
Other brands: Fuzeon