Generic Name: Factor IX (Recombinant [Fc Fusion Protein]) (FAK tor nyne ree KOM be nant eff see FYOO zhun PRO teen)
Brand Name: Alprolix
Medically reviewed on Feb 15, 2019
Uses of Alprolix:
- It is used to treat hemophilia.
- It is used to treat or prevent bleeding.
What do I need to tell my doctor BEFORE I take Alprolix?
- If you have an allergy to Alprolix (factor IX (recombinant [fc fusion protein])) or any part of Alprolix (factor IX (recombinant [fc fusion protein])).
- If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
This medicine may interact with other drugs or health problems.
Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take Alprolix (factor IX (recombinant [fc fusion protein])) with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
What are some things I need to know or do while I take Alprolix?
- Tell all of your health care providers that you take Alprolix (factor IX (recombinant [fc fusion protein])). This includes your doctors, nurses, pharmacists, and dentists.
- Allergic side effects may rarely happen.
- Blood clots have happened with Alprolix (factor IX (recombinant [fc fusion protein])). Tell your doctor if you have ever had a blood clot. Talk with your doctor.
- Have blood work checked as you have been told by the doctor. Talk with the doctor.
- Call the doctor right away if the normal dose does not work as well.
- Tell your doctor if you are pregnant or plan on getting pregnant. You will need to talk about the benefits and risks of using Alprolix (factor IX (recombinant [fc fusion protein])) while you are pregnant.
- Tell your doctor if you are breast-feeding. You will need to talk about any risks to your baby.
How is this medicine (Alprolix) best taken?
Use Alprolix (factor IX (recombinant [fc fusion protein])) as ordered by your doctor. Read all information given to you. Follow all instructions closely.
- It is given as a shot into a vein.
- If you will be giving yourself the shot, your doctor or nurse will teach you how to give the shot.
- Follow how to use as you have been told by the doctor or read the package insert.
- Wash your hands before and after use.
- This medicine needs to be mixed before use. Follow how to mix as you were told by the doctor.
- If stored in a refrigerator, let Alprolix (factor IX (recombinant [fc fusion protein])) come to room temperature before mixing. Do not heat Alprolix (factor IX (recombinant [fc fusion protein])).
- Do not shake.
- After mixing, you may store at room temperature for 3 hours.
- After mixing, do not refrigerate.
- Do not use if the solution is cloudy, leaking, or has particles.
- Do not use if solution changes color.
- Throw away needles in a needle/sharp disposal box. Do not reuse needles or other items. When the box is full, follow all local rules for getting rid of it. Talk with a doctor or pharmacist if you have any questions.
What do I do if I miss a dose?
- Call your doctor to find out what to do.
What are some side effects that I need to call my doctor about right away?
WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect:
- Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat; trouble breathing, swallowing, or talking; unusual hoarseness; or swelling of the mouth, face, lips, tongue, or throat.
- Signs of kidney problems like unable to pass urine, change in how much urine is passed, blood in the urine, or a big weight gain.
- A burning, numbness, or tingling feeling that is not normal.
- Upset stomach or throwing up.
- Shortness of breath.
- Dizziness or passing out.
- Call your doctor right away if you have signs of a blood clot like chest pain or pressure; coughing up blood; shortness of breath; swelling, warmth, numbness, change of color, or pain in a leg or arm; or trouble speaking or swallowing.
What are some other side effects of Alprolix?
All drugs may cause side effects. However, many people have no side effects or only have minor side effects. Call your doctor or get medical help if any of these side effects or any other side effects bother you or do not go away:
- Numbness or tingling in the mouth.
These are not all of the side effects that may occur. If you have questions about side effects, call your doctor. Call your doctor for medical advice about side effects.
You may report side effects to the FDA at 1-800-FDA-1088. You may also report side effects at http://www.fda.gov/medwatch.
If OVERDOSE is suspected:
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
How do I store and/or throw out Alprolix?
- Store in a refrigerator. Do not freeze.
- Store in the carton to protect from light.
- If needed, you may store at room temperature.
- If stored at room temperature, make a note of the date it was placed at room temperature.
- If stored at room temperature, throw away any unused vials after 6 months or after the expiration date, whichever comes first.
- Do not put Alprolix (factor IX (recombinant [fc fusion protein])) back in the refrigerator after it has been stored at room temperature.
- Store in a dry place. Do not store in a bathroom.
- Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
- Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.
Consumer information use
- If your symptoms or health problems do not get better or if they become worse, call your doctor.
- Do not share your drugs with others and do not take anyone else's drugs.
- Keep a list of all your drugs (prescription, natural products, vitamins, OTC) with you. Give this list to your doctor.
- Talk with the doctor before starting any new drug, including prescription or OTC, natural products, or vitamins.
- Some drugs may have another patient information leaflet. Check with your pharmacist. If you have any questions about Alprolix (factor IX (recombinant [fc fusion protein])), please talk with your doctor, nurse, pharmacist, or other health care provider.
- If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
More about Alprolix (coagulation factor ix)
- Alprolix Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Pricing & Coupons
- En Español
- Drug class: miscellaneous coagulation modifiers