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Nimodipine use while Breastfeeding

Medically reviewed by Last updated on Apr 17, 2023.

Drugs containing Nimodipine: Nimotop, Nymalize

Nimodipine Levels and Effects while Breastfeeding

Summary of Use during Lactation

Based on limited data, amounts ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.

Drug Levels

Maternal Levels. A woman who was 3 days postpartum received 60 mg of nimodipine orally every 4 hours. She had a peak milk nimodipine level of about 3.5 mcg/L at 1 hour after a dose at steady-state. Milk levels from 1 hour before a dose (i.e., 3 hours after the previous dose) to simultaneously with a dose were less than 1 mcg/L.[1] Using the peak milk level data, the estimated maximum intake of an exclusively breastfed infant would be about 0.0009% of the maternal weight-adjusted dosage.

One woman who was 3 weeks postpartum was receiving nimodipine 2 mg per hour intravenously for 22 hours. The highest milk nimodipine concentration occurred 2 hours after completing the regimen and was 4.7 mcg/L. Four hours later the level had dropped to 0.63 mcg/L. It was estimated that a nursing infant would receive a maximum daily dosage of 0.092% of the mother's weight-adjusted dosage.[2]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.


Tonks AM. Nimodipine levels in breast milk. Aust N Z J Surg. 1995;65:693–4. [PubMed: 7575306]
Carcas AJ, Abad-Santos F, de Rosendo JM, et al. Nimodipine transfer into human breast milk and cerebrospinal fluid. Ann Pharmacother. 1996;30:148–50. [PubMed: 8835048]

Substance Identification

Substance Name


CAS Registry Number


Drug Class

Breast Feeding


Antihypertensive Agents

Calcium Channel Blockers

Vasodilator Agents

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Further information

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