Methyclothiazide Levels and Effects while Breastfeeding
Summary of Use during Lactation
No information is available on the amount of methyclothiazide in breastmilk. Intense diuresis with large doses may decrease breastmilk production. Other diuretics in low doses are preferred over methyclothiazide.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information on methyclothiazide was not found as of the revision date. Intense diuresis with thiazides and thiazide-like diuretics, fluid restriction and breast binding have been used to suppress postpartum lactation.[1-3] The added contribution of the diuretic to these measures, which are effective in suppressing lactation, has not been studied. There are no data on the effects of diuretics on established, ongoing lactation.
Healy M. Suppressing lactation with oral diuretics. Lancet 1961;1:1353-4.doi:10.1016/S0140-6736(61)90289-6 [CrossRef]
2.
Reiher KH. Suppression of lactation by stimulation of diuresis. Zentralbl Gynakol 1963;85:188-90 [PubMed: 13973786]
3.
Stout G. Suppression of lactation. Br Med J 1962;1:1150
Substance Identification
Substance Name
Methyclothiazide
CAS Registry Number
135-07-9
Drug Class
Breast Feeding
Lactation
Milk, Human
Antihypertensive Agents
Thiazide Diuretics
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