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Docusate use while Breastfeeding

Drugs containing Docusate: Colace, DOK, Dulcolax Stool Softener, Senna S, Senna Plus, Senokot S, Surfak, Colace 2-in-1, DSS, Senexon-S, Show all 106 »Docu, Enemeez Mini, Peri-Colace, Doculax, Dok Plus, Sulfolax, Surfak Stool Softener, Doc-Q-Lace, Calcium Stool Softener, Phillips Stool Softener, Diocto, Ferro-Sequels (old formulation), Doculase, DOS, Silace, Docuzen, Sennalax-S, Laxacin, Dialose, Regulax SS, Dionex, Fe-Stool, Ferro Basic, Ferro-Caps, Ferrous DS, Ferocyl, Kao-Tin, Ex-Lax Extra Gentle, Vacuant, Pedia-Lax Stool Softener, DocuSol Kids, Pedia-Lax Liquid Stool Softener, Promolaxin, Docusil, Ferro-DSS, Docusol Plus, Dialose Plus, Docucal-P, Doxidan Softgel Laxative Plus Stool Softener, Femilax, Feminine Lax, Femintrol, Modane Plus, Phillips Gel, DocuSol, Unilax, Medi-Laxx, Senna-Time S, Gentlax S, Ex-Lax Gentle Strength, SenoSol-SS, Kaopectate Stool Softener, Ex-Lax Stool Softener, Octycine-250, DSMC Compound Plain, DC-240, Doculax Plus, Strong Caps, Peri-DS, Peri-DOS, Perestan, Genasoft Plus, DSS Plus, Aqualax Forte, Sulfalax Calcium, Octycine, Docu Soft Plus, Diocto-K Plus, Dioctolose, Diocto-C, Doxidan, Enemeez Plus, Therevac Plus, Kasof, Modane Soft, Octycine-100, D-S Caps, Therevac-SB, Correctol Softgel Extra Gentle, Colace Micro-Enema, Fleet Sof-Lax Stool Softener, Doss-Relief, Sur-Q-Lax, Genasoft, Vacuant Plus, Calube, Dioeze, Docusoft S, Docucal, Docu Soft, Docuprene, Dioctyn, Dioctosoftez, Dioctocal, Aqualax, Doc-Q-Lax

Medically reviewed by Last updated on Feb 6, 2021.

Docusate Levels and Effects while Breastfeeding

Summary of Use during Lactation

Docusate is minimally absorbed from the gastrointestinal tract and therefore the drug is unlikely to be found in the maternal serum or breastmilk. Laxatives that are completely unabsorbed may be preferred.[1]

Drug Levels

Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

In a randomized, blinded trial, 35 postpartum breastfeeding patients received a laxative containing docusate in a dose of 120 mg daily in addition to danthron 100 mg daily. One patient stated that diarrhea occurred in her breastfed infant.[2] The diarrhea was most likely caused by the danthron.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Bisacodyl, Magnesium Hydroxide, Psyllium, Senna


Lewis JH, Weingold AB., Committee of FDA-Related Matters American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912–23. [PubMed: 2864852]
Greenhalf JO, Leonard HS. Laxatives in the treatment of constipation in pregnant and breast-feeding mothers. Practitioner. 1973;210:259–63. [PubMed: 4570522]

Substance Identification

Substance Name


CAS Registry Number


Drug Class

Breast Feeding


Gastrointestinal Agents


Surface-Active Agents

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Further information

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