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Docusate use while Breastfeeding

Drugs containing Docusate: Colace, Senna S, DOK, Dulcolax Stool Softener, Doc-Q-Lace, Senna Plus, Peri-Colace, Senokot S, Senexon-S, Surfak, Show all 102 »Doculase, Doculax, DSS, Phillips Stool Softener, Enemeez Mini, Silace, Sennalax-S, DOS, Calcium Stool Softener, Promolaxin, Ferrous DS, Colace Micro-Enema, Doxidan, Doc-Q-Lax, Docusil, Dok Plus, Surfak Stool Softener, Diocto, Sulfolax, Ferro-Sequels (old formulation), Ferro Basic, Laxacin, Kao-Tin, Kaopectate Stool Softener, Modane Soft, Docuprene, Ferocyl, Octycine-100, Vacuant, Fe-Stool, Octycine-250, DocuSol Kids, DocuSol, Pedia-Lax Stool Softener, Pedia-Lax Liquid Stool Softener, Ferro-Caps, Docusol Plus, Ferro-DSS, Ex-Lax Extra Gentle, Dialose Plus, Docucal-P, Doxidan Softgel Laxative Plus Stool Softener, Femilax, Feminine Lax, Correctol Softgel Extra Gentle, Femintrol, Modane Plus, Phillips Gel, Unilax, Gentlax S, Ex-Lax Gentle Strength, Therevac-SB, Dionex, Fleet Sof-Lax Stool Softener, DSMC Compound Plain, Doculax Plus, Strong Caps, Peri-DS, Peri-DOS, Perestan, Genasoft Plus, DSS Plus, Aqualax Forte, DC-240, Octycine, Docu Soft Plus, Diocto-K Plus, Dioctolose, Diocto-C, Enemeez Plus, Therevac Plus, Dialose, Kasof, Doss-Relief, Docu Soft, Sur-Q-Lax, Genasoft, Ex-Lax Stool Softener, D-S Caps, Calube, Docusoft S, Docucal, Docu, Sulfalax Calcium, Vacuant Plus, Dioctyn, Dioctosoftez, Dioctocal, Aqualax, Dioeze, Regulax SS, SenoSol-SS

Medically reviewed on Sep 7, 2018

Docusate Levels and Effects while Breastfeeding

Summary of Use during Lactation

Docusate is minimally absorbed from the gastrointestinal tract and therefore the drug is unlikely to be found in the maternal serum or breastmilk. Laxatives that are completely unabsorbed may be preferred.[2]

Drug Levels

Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

In a randomized, blinded trial, 35 postpartum breastfeeding patients received a laxative containing docusate in a dose of 120 mg daily in addition to danthron 100 mg daily. One patient stated that diarrhea occurred in her breastfed infant.[1] The diarrhea was most likely caused by the danthron.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Bisacodyl, Magnesium Hydroxide, Psyllium, Senna


1. Greenhalf JO, Leonard HS. Laxatives in the treatment of constipation in pregnant and breast-feeding mothers. Practitioner. 1973;210:259-63. PMID: 4570522

2. Lewis JH, Weingold AB and the Committee of FDA-Related Matters, American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912-23. PMID: 2864852

Docusate Identification

Substance Name


CAS Registry Number


Drug Class

Gastrointestinal Agents


Surface-Active Agents

Administrative Information

LactMed Record Number



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Further information

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