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Docusate use while Breastfeeding

Drugs containing Docusate: Colace, DOK, Senna Plus, Dulcolax Stool Softener, Senna S, Doc-Q-Lace, Senokot S, Peri-Colace, Surfak, DSS, Show all 102 »Senexon-S, Sennalax-S, Enemeez Mini, Silace, Docuprene, Doculax, Colace Micro-Enema, Dok Plus, Doculase, Calube, Calcium Stool Softener, Octycine-250, Phillips Stool Softener, Docusoft S, Pedia-Lax Stool Softener, Promolaxin, Docusil, Diocto, DocuSol, Docu, Ferro-DSS, Ferro-Sequels (old formulation), Ferocyl, Fe-Stool, DocuSol Kids, Vacuant, Pedia-Lax Liquid Stool Softener, Kao-Tin, Kaopectate Stool Softener, Sulfolax, Octycine-100, Ferrous DS, Ferro-Caps, Ferro Basic, Docusol Plus, Ex-Lax Extra Gentle, Dialose Plus, Docucal-P, Doxidan Softgel Laxative Plus Stool Softener, Femilax, Correctol Softgel Extra Gentle, Feminine Lax, Femintrol, Modane Plus, Phillips Gel, Unilax, Gentlax S, Ex-Lax Gentle Strength, SenoSol-SS, Doc-Q-Lax, Therevac-SB, Dioctocal, Fleet Sof-Lax Stool Softener, Aqualax Forte, Strong Caps, Peri-DS, Peri-DOS, Perestan, Genasoft Plus, DSS Plus, DSMC Compound Plain, Octycine, Dialose, Docu Soft Plus, Diocto-K Plus, Dioctolose, Diocto-C, Doxidan, Enemeez Plus, Therevac Plus, Doculax Plus, Surfak Stool Softener, Doss-Relief, Dioctyn, Sur-Q-Lax, Genasoft, Ex-Lax Stool Softener, D-S Caps, Docucal, Docu Soft, Dionex, Dioctosoftez, DC-240, Vacuant Plus, Aqualax, Dioeze, Regulax SS, Modane Soft, DOS, Sulfalax Calcium, Kasof, Laxacin

Medically reviewed by Last updated on Apr 30, 2019.

Docusate Levels and Effects while Breastfeeding

Summary of Use during Lactation

Docusate is minimally absorbed from the gastrointestinal tract and therefore the drug is unlikely to be found in the maternal serum or breastmilk. Laxatives that are completely unabsorbed may be preferred.[2]

Drug Levels

Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

In a randomized, blinded trial, 35 postpartum breastfeeding patients received a laxative containing docusate in a dose of 120 mg daily in addition to danthron 100 mg daily. One patient stated that diarrhea occurred in her breastfed infant.[1] The diarrhea was most likely caused by the danthron.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Bisacodyl, Magnesium Hydroxide, Psyllium, Senna


1. Greenhalf JO, Leonard HS. Laxatives in the treatment of constipation in pregnant and breast-feeding mothers. Practitioner. 1973;210:259-63. PMID: 4570522

2. Lewis JH, Weingold AB and the Committee of FDA-Related Matters, American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912-23. PMID: 2864852

Docusate Identification

Substance Name


CAS Registry Number


Drug Class

Breast Feeding


Gastrointestinal Agents


Surface-Active Agents

Administrative Information

LactMed Record Number



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Further information

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