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Docusate use while Breastfeeding

Drugs containing Docusate: Colace, DOK, Senna S, Dulcolax Stool Softener, Senna Plus, Surfak, Peri-Colace, DSS, Silace, Doc-Q-Lace, Show all 105 »Senokot S, Dok Plus, Enemeez Mini, Senexon-S, Sennalax-S, Diocto, Dialose, DocuSol, Aqualax, Calcium Stool Softener, Calube, Phillips Stool Softener, Doculase, Pedia-Lax Stool Softener, Promolaxin, Ferro-Sequels (old formulation), Ferocyl, Docusol Plus, DOS, Doculax, Laxacin, Phillips Gel, Fe-Stool, Sulfolax, Kaopectate Stool Softener, Kao-Tin, Pedia-Lax Liquid Stool Softener, Docusil, Vacuant, DocuSol Kids, SenoSol-SS, Ex-Lax Gentle Strength, Ferrous DS, Ferro-Caps, Ferro Basic, Ex-Lax Extra Gentle, Ferro-DSS, Octycine-100, Dialose Plus, Docucal-P, Doxidan Softgel Laxative Plus Stool Softener, Femilax, Feminine Lax, Femintrol, Modane Plus, Gentlax S, Senna-Time S, Medi-Laxx, Docuzen, Unilax, Octycine-250, Docucal, Therevac-SB, DSMC Compound Plain, Surfak Stool Softener, Doculax Plus, Strong Caps, Peri-DS, Peri-DOS, Perestan, Genasoft Plus, DSS Plus, Aqualax Forte, Kasof, Octycine, Docu Soft Plus, Diocto-K Plus, Dioctolose, Diocto-C, Doxidan, Enemeez Plus, Therevac Plus, DC-240, Sulfalax Calcium, Correctol Softgel Extra Gentle, Vacuant Plus, Colace Micro-Enema, Fleet Sof-Lax Stool Softener, Doss-Relief, Sur-Q-Lax, Genasoft, Ex-Lax Stool Softener, D-S Caps, Docusoft S, Docu Soft, Modane Soft, Docuprene, Docu, Dionex, Dioctyn, Dioctosoftez, Dioctocal, Dioeze, Regulax SS, Doc-Q-Lax

Medically reviewed by Last updated on Jan 6, 2020.

Docusate Levels and Effects while Breastfeeding

Summary of Use during Lactation

Docusate is minimally absorbed from the gastrointestinal tract and therefore the drug is unlikely to be found in the maternal serum or breastmilk. Laxatives that are completely unabsorbed may be preferred.[2]

Drug Levels

Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

In a randomized, blinded trial, 35 postpartum breastfeeding patients received a laxative containing docusate in a dose of 120 mg daily in addition to danthron 100 mg daily. One patient stated that diarrhea occurred in her breastfed infant.[1] The diarrhea was most likely caused by the danthron.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Bisacodyl, Magnesium Hydroxide, Psyllium, Senna


1. Greenhalf JO, Leonard HS. Laxatives in the treatment of constipation in pregnant and breast-feeding mothers. Practitioner. 1973;210:259-63. PMID: 4570522

2. Lewis JH, Weingold AB and the Committee of FDA-Related Matters, American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912-23. PMID: 2864852

Docusate Identification

Substance Name


CAS Registry Number


Drug Class

Breast Feeding


Gastrointestinal Agents


Surface-Active Agents

Administrative Information

LactMed Record Number



Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Further information

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