Skip to main content

Docusate use while Breastfeeding

Medically reviewed by Last updated on Jun 29, 2023.

Drugs containing Docusate: Colace, Docu, Dulcolax Stool Softener, Senna Plus, Senna S, Senexon-S, Senokot S, Colace 2-in-1, Surfak, DOK, Show all 106 »DSS, Regulax SS, Doculase, Promolaxin, Docuzen, Senna-Time S, Peri-Colace, Surfak Stool Softener, Docuprene, Colace Micro-Enema, Enemeez Mini, Doculax, Enemeez Plus, Doc-Q-Lace, Docusil, Ferro-Sequels (old formulation), Dok Plus, Sennalax-S, Doc-Q-Lax, Laxacin, Docusol Plus, Vacuant Plus, Therevac Plus, Doxidan, Diocto-C, Dioctolose, Diocto-K Plus, Docu Soft Plus, Octycine, Aqualax Forte, DSMC Compound Plain, DSS Plus, Genasoft Plus, Perestan, Peri-DOS, Peri-DS, Strong Caps, Doculax Plus, Dialose, DC-240, Kasof, Sulfalax Calcium, DOS, Modane Soft, Dioeze, Aqualax, Dioctocal, Dioctosoftez, Dioctyn, Dionex, Docu Soft, Docucal, Docusoft S, Calcium Stool Softener, Calube, D-S Caps, Ex-Lax Stool Softener, Genasoft, Sur-Q-Lax, Doss-Relief, Silace, Fleet Sof-Lax Stool Softener, Correctol Softgel Extra Gentle, Therevac-SB, Octycine-100, Octycine-250, Phillips Stool Softener, Sulfolax, DocuSol, Kaopectate Stool Softener, Kao-Tin, Pedia-Lax Stool Softener, Pedia-Lax Liquid Stool Softener, Vacuant, DocuSol Kids, Diocto, Ferocyl, Ferrous DS, Ferro-Caps, Ferro Basic, Fe-Stool, Ferro-DSS, Ex-Lax Extra Gentle, Dialose Plus, Docucal-P, Doxidan Softgel Laxative Plus Stool Softener, Femilax, Feminine Lax, Femintrol, Modane Plus, Phillips Gel, Unilax, Medi-Laxx, Gentlax S, Ex-Lax Gentle Strength, SenoSol-SS

Docusate Levels and Effects while Breastfeeding

Summary of Use during Lactation

Docusate is minimally absorbed from the gastrointestinal tract and therefore the drug is unlikely to be found in the maternal serum or breastmilk. Laxatives that are completely unabsorbed may be preferred.[1]

Drug Levels

Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

In a randomized, blinded trial, 35 postpartum breastfeeding patients received a laxative containing docusate in a dose of 120 mg daily in addition to danthron 100 mg daily. One patient stated that diarrhea occurred in her breastfed infant.[2] The diarrhea was most likely caused by the danthron.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Bisacodyl, Magnesium Hydroxide, Psyllium, Senna


Lewis JH, Weingold AB., Committee of FDA-Related Matters American College of Gastroenterology. The use of gastrointestinal drugs during pregnancy and lactation. Am J Gastroenterol. 1985;80:912–23. [PubMed: 2864852]
Greenhalf JO, Leonard HS. Laxatives in the treatment of constipation in pregnant and breast-feeding mothers. Practitioner. 1973;210:259–63. [PubMed: 4570522]

Substance Identification

Substance Name


CAS Registry Number


Drug Class

Breast Feeding


Gastrointestinal Agents


Surface-Active Agents

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.