Bisacodyl use while Breastfeeding
Drugs containing Bisacodyl: Dulcolax, Dulcolax Laxative, Correctol, Bisacodyl Uniserts, Bisac-Evac, Bisolax, Laxative Gentle Suppositories, Colax, Modane, Gentle Laxative, Show all 36 »
Medically reviewed by Drugs.com. Last updated on Apr 20, 2019.
Bisacodyl Levels and Effects while Breastfeeding
Summary of Use during Lactation
Bisacodyl is not absorbed from the gastrointestinal tract, and its active metabolite, which is absorbed, is not detectable in breastmilk. Bisacodyl can be taken during breastfeeding and no special precautions are required.
Drug Levels
Maternal Levels. Sixteen postpartum women who were not breastfeeding, but were producing at least 200 mL of milk daily by breast pump were given either oral enteric-coated bisacodyl tablets (Dulcolax) 10 mg daily or oral liquid sodium picosulfate (Laxoberal) 10 mg daily for 7 days. Both drugs are prodrugs metabolized to the active drug, bis-(p-hydroxyphenyl)-2-pyridyl-2-methane (BHPM). All breastmilk was collected daily from the day before drug administration to 2 days after the last dose. Free and conjugated BHPM were undetectable (<1 mcg/L) in all milk samples.[1]
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information was not found as of the revision date.
Alternate Drugs to Consider
Docusate, Magnesium Hydroxide, Psyllium, Senna
References
1. Friedrich C, Richter E, Trommeshauser D et al. Lack of excretion of the active moiety of bisacodyl and sodium picosulfate into human breast milk: an open-label, parallel group, multiple dose study in healthy lactating women. Drug Metab Pharmacokinet. 2011;26:458-64. PMID: 21697613
Bisacodyl Identification
Substance Name
Bisacodyl
CAS Registry Number
603-50-9
Drug Class
Breast Feeding
Lactation
Cathartics
Gastrointestinal Agents
Administrative Information
LactMed Record Number
448
Disclaimer
Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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Consumer resources
Other brands: Dulcolax, Correctol, Fleet Bisacodyl, Bisa-Lax
