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Bisacodyl use while Breastfeeding

Drugs containing Bisacodyl: Dulcolax, Dulcolax Laxative, Correctol, Alophen, Doxidan Tablet, Fleet Bisacodyl, Ducodyl, Bisa-Lax, Bisco-Lax, HalfLytely and Bisacodyl, Show all 36 »Carter's Little Pills, Modane, Bisolax, Bisac-Evac, Dulcogen, Bisacodyl Uniserts, Evac-U-Gen, Fleet Prep Kit 2, Fleet Prep Kit 1, Dulcolax Bowel Cleansing, Evac-Q-Kwik, Tridate, Royvac Bowel Evacuant, LoSo Prep Bowel Cleansing System, Ex-lax Ultra, Colax, Laxative Gentle Suppositories, Gentle Laxative, Gen Lax, Bisa-Plex, Fematrol, Veracolate, Gentlax Tablet, Feen-A-Mint, Magic Bullet, Fleet Prep Kit 3

Medically reviewed by Last updated on May 5, 2019.

Bisacodyl Levels and Effects while Breastfeeding

Summary of Use during Lactation

Bisacodyl is not absorbed from the gastrointestinal tract, and its active metabolite, which is absorbed, is not detectable in breastmilk. Bisacodyl can be taken during breastfeeding and no special precautions are required.

Drug Levels

Maternal Levels. Sixteen postpartum women who were not breastfeeding, but were producing at least 200 mL of milk daily by breast pump were given either oral enteric-coated bisacodyl tablets (Dulcolax) 10 mg daily or oral liquid sodium picosulfate (Laxoberal) 10 mg daily for 7 days. Both drugs are prodrugs metabolized to the active drug, bis-(p-hydroxyphenyl)-2-pyridyl-2-methane (BHPM). All breastmilk was collected daily from the day before drug administration to 2 days after the last dose. Free and conjugated BHPM were undetectable (<1 mcg/L) in all milk samples.[1]

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information was not found as of the revision date.

Alternate Drugs to Consider

Docusate, Magnesium Hydroxide, Psyllium, Senna


1. Friedrich C, Richter E, Trommeshauser D et al. Lack of excretion of the active moiety of bisacodyl and sodium picosulfate into human breast milk: an open-label, parallel group, multiple dose study in healthy lactating women. Drug Metab Pharmacokinet. 2011;26:458-64. PMID: 21697613

Bisacodyl Identification

Substance Name


CAS Registry Number


Drug Class

Breast Feeding



Gastrointestinal Agents

Administrative Information

LactMed Record Number



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Further information

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