It is unknown if bumetanide is excreted into breastmilk. It should be avoided while breastfeeding a newborn because it may decrease milk flow or completely suppress lactation. Low doses in mothers whose lactation is well established are unlikely to suppress lactation. In general, alternate drugs are preferred.
Drug Levels
Maternal Levels. Relevant published information was not found as of the revision date.
Infant Levels. Relevant published information was not found as of the revision date.
Effects in Breastfed Infants
Relevant published information was not found as of the revision date.
Effects on Lactation and Breastmilk
Relevant published information on bumetanide was not found as of the revision date. Intense diuresis, fluid restriction and breast binding have been used to suppress lactation immediately postpartum.[1-4] The added contribution of the diuretic to the other measures, which are effective in suppressing lactation, has not been studied. No data exist on the effects of loop diuretics on established, ongoing lactation.
Healy M. Suppressing lactation with oral diuretics. Lancet 1961;1:1353-4. doi:10.1016/S0140-6736(61)90289-6 [CrossRef]
2.
Stout G. Suppression of lactation. Br Med J 1962;1:1150.
3.
Reiher KH. [Suppression of lactation by stimulation of diuresis]. Zentralbl Gynakol 1963;85:188-90. [PubMed: 13973786]
4.
Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J 1976;50:251-2. [PubMed: 3858]
Substance Identification
Substance Name
Bumetanide
CAS Registry Number
28395-03-1
Drug Class
Breast Feeding
Lactation
Milk, Human
Antihypertensive Agents
Loop Diuretics
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.
