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Bumetanide use while Breastfeeding

Drugs containing Bumetanide: Bumex

Bumetanide Levels and Effects while Breastfeeding

Summary of Use during Lactation

It is unknown if bumetanide is excreted into breastmilk. It should be avoided while breastfeeding a newborn because it may decrease milk flow or completely suppress lactation. Low doses in mothers whose lactation is well established are unlikely to suppress lactation. In general, alternate drugs are preferred.

Drug Levels

Maternal Levels. Relevant published information was not found as of the revision date.

Infant Levels. Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Relevant published information on bumetanide was not found as of the revision date. Intense diuresis, fluid restriction and breast binding have been used to suppress lactation immediately postpartum.[1][2][3] The added contribution of the diuretic to the other measures, which are effective in suppressing lactation, has not been studied. No data exist on the effects of loop diuretics on established, ongoing lactation.

Alternate Drugs to Consider

Chlorothiazide, Hydrochlorothiazide

References

1. Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;1:1353-4.

2. Stout G. Suppression of lactation. Br Med J. 1962;1:1150. Letter. PMC: PMC1958377

3. Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J. 1976;50:251-2. PMID: 3858

Bumetanide Identification

Substance Name

Bumetanide

CAS Registry Number

28395-03-1

Drug Class

Antihypertensive Agents

Loop Diuretics

Administrative Information

LactMed Record Number

36

Last Revision Date

20150310

Disclaimer

Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. The U.S. government does not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.

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