Amiloride use while Breastfeeding

Medically reviewed by Drugs.com. Last updated on May 26, 2022.

Drugs containing Amiloride: Moduretic, Midamor, Moduretic 5-50

Amiloride Levels and Effects while Breastfeeding

Summary of Use during Lactation

No information is available on the use of amiloride during breastfeeding, so an alternate drug may be preferred.

Drug Levels

Relevant published information was not found as of the revision date.

Effects in Breastfed Infants

Relevant published information was not found as of the revision date.

Effects on Lactation and Breastmilk

Intense diuresis can suppress lactation;[1,2] however, it is unlikely that amiloride alone is sufficiently potent to cause this effect.

Alternate Drugs to Consider

Spironolactone

References

1.: Healy M. Suppressing lactation with oral diuretics. Lancet. 1961;1:1353–4. [CrossRef]
2.: Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J 1976;50:251-2. PMID: 3858. [PubMed: 3858]

Substance Identification

Substance Name

Amiloride

CAS Registry Number

2609-46-3

Drug Class

Breast Feeding

Lactation

Diuretics

1.: Healy M. Suppressing lactation with oral diuretics. Lancet 1961;1:1353-4. doi:10.1016/S0140-6736(61)90289-6
2.: Cominos DC, Van Der Walt A, Van Rooyen AJ. Suppression of postpartum lactation with furosemide. S Afr Med J 1976;50:251-2. PMID: 3858

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