Generic Nascobal Availability
Last updated on Oct 9, 2024.
Nascobal is a brand name of cyanocobalamin, approved by the FDA in the following formulation(s):
NASCOBAL (cyanocobalamin - gel, metered;nasal)
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Manufacturer: ENDO OPERATIONS
Approval date: November 5, 1996
Strength(s): 0.5MG/INH (discontinued)
NASCOBAL (cyanocobalamin - spray, metered;nasal)
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Manufacturer: ENDO OPERATIONS
Approval date: January 31, 2005
Strength(s): 0.5MG/SPRAY (discontinued) [RLD]
All of the above formulations have been discontinued.
Note: Fraudulent online pharmacies may attempt to sell an illegal generic version of Nascobal. These medications may be counterfeit and potentially unsafe. If you purchase medications online, be sure you are buying from a reputable and valid online pharmacy. Ask your health care provider for advice if you are unsure about the online purchase of any medication.
See also: Generic Drug FAQ.
Related patents
Patents are granted by the U.S. Patent and Trademark Office at any time during a drug's development and may include a wide range of claims.
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Patent 7,229,636
Patent expiration dates:
- August 1, 2024✓✓
- August 1, 2024
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Patent 7,404,489
Patent expiration dates:
- March 12, 2024✓
- March 12, 2024
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Patent 7,879,349
Patent expiration dates:
- August 1, 2024✓✓
- August 1, 2024
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Patent 8,003,353
Patent expiration dates:
- August 1, 2024✓
- August 1, 2024
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Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
Patent 8,940,714
Issued: January 27, 2015
Inventor(s): Quay Steven C. & Aprile Peter C. & Go Zenaida O. & Sileno Anthony P.
Assignee(s): Par Pharmaceutical, Inc.A stable pharmaceutical mercury-free aqueous solution of cyanocobalamin comprised of cyanocobalamin and water wherein said solution of cyanocobalamin is suitable for intranasal administration, has a viscosity less than about 1000 cPs, and wherein said solution of cyanocobalamin has a bioavailability of cyanocobalamin when administered intranasally of at least about 7% relative to an intramuscular injection of cyanocobalamin with the proviso that the solution is essentially free of mercury and mercury-containing compounds. The present invention is also directed towards a method for elevating the vitamin B12 levels in the cerebral spinal fluid (CSF) comprising administering intranasally a sufficient amount of a mercury-free cyanocobalamin solution so as to increase the average ratio of vitamin B12 in the CSF to that in the blood serum (B12 CSF/B12 Serum×100) to at least about 1.1 comprising intranasally administering an aqueous solution of a cyanocobalamin, wherein said solution of cyanocobalamin has a bioavailability of at least 7% relative to an intramuscular injection of a cyanocobalamin.
Patent expiration dates:
- February 26, 2024✓
- February 26, 2024
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Cyanocobalamin low viscosity aqueous formulations for intranasal delivery
Patent 9,415,007
Issued: August 16, 2016
Inventor(s): Quay Steven C. & Aprile Peter C. & Go Zenaida O. & Sileno Anthony P.
Assignee(s): PAR PHARMACEUTICAL, INC.A stable pharmaceutical mercury-free aqueous solution of cyanocobalamin comprised of cyanocobalamin and water wherein said solution of cyanocobalamin is suitable for intranasal administration, has a viscosity less than about 1000 cPs, and wherein said solution of cyanocobalamin has a bioavailability of cyanocobalamin when administered intranasally of at least about 7% relative to an intramuscular injection of cyanocobalamin with the proviso that the solution is essentially free of mercury and mercury-containing compounds. The present invention is also directed towards a method for elevating the vitamin B12 levels in the cerebral spinal fluid (CSF) comprising administering intranasally a sufficient amount of a mercury-free cyanocobalamin solution so as to increase the average ratio of vitamin B12 in the CSF to that in the blood serum (B12 CSF/B12 Serum×100) to at least about 1.1 comprising intranasally administering an aqueous solution of a cyanocobalamin, wherein said solution of cyanocobalamin has a bioavailability of at least 7% relative to an intramuscular injection of a cyanocobalamin.
Patent expiration dates:
- July 28, 2024✓
- July 28, 2024
More about Nascobal (cyanocobalamin)
- Nascobal consumer information
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- Pricing & coupons
- Reviews (1)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: vitamins
- En español
Related treatment guides
Glossary
Term | Definition |
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Drug Patent | A drug patent is assigned by the U.S. Patent and Trademark Office and assigns exclusive legal right to the patent holder to protect the proprietary chemical formulation. The patent assigns exclusive legal right to the inventor or patent holder, and may include entities such as the drug brand name, trademark, product dosage form, ingredient formulation, or manufacturing process A patent usually expires 20 years from the date of filing, but can be variable based on many factors, including development of new formulations of the original chemical, and patent infringement litigation. |
Drug Exclusivity | Exclusivity is the sole marketing rights granted by the FDA to a manufacturer upon the approval of a drug and may run simultaneously with a patent. Exclusivity periods can run from 180 days to seven years depending upon the circumstance of the exclusivity grant. |
RLD | A Reference Listed Drug (RLD) is an approved drug product to which new generic versions are compared to show that they are bioequivalent. A drug company seeking approval to market a generic equivalent must refer to the Reference Listed Drug in its Abbreviated New Drug Application (ANDA). By designating a single reference listed drug as the standard to which all generic versions must be shown to be bioequivalent, FDA hopes to avoid possible significant variations among generic drugs and their brand name counterpart. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.