I re-started my zoloft 7 weeks ago - i have done 2 weeks at 25mg and 4 weeks (Saturday will be my fifth week) at 50 mg. I suffer from existential OCD. I have had the typical side effects - night sweats, blurry vision, and some brain fog. However, i notice i can go even a few more minutes in between OCD episodes. Do you think the Zoloft is starting to work and to hang in the next two weeks or should i ask for an increase because it should be a lot more in between thoughts. I have heard that although they are annoying side effects are a good sign your medication is working. I am hoping i will turn the corner soon and that it is a little bit of a two step forward one back approach.