I am allergic to albuterol sulfate, it causes numbing of my mouth/nose if I use the HFA inhalers more than 3-4 times in a week. I have tried symbicort, seravent, ventolin, proair inhalers as my everyday inhalers and all have the same result of numbness within 3-4 days of daily use. I was on Advair diskus 500/50 until my insurance company took Advair off of my acceptable drug list.